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Clinical Impact of Polygenic Risk Score for Breast Cancer Risk Prediction in 382 Individuals with Hereditary Breast and Ovarian Cancer Syndrome
SIMPLE SUMMARY: Breast cancer (BC) is the major cause of cancer-related deaths in women worldwide. In addition to genetic diagnostics for variants in high-risk genes, there is a need for better risk stratification to target high-risk individuals. The polygenic risk score (PRS) has emerged as a valua...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10417109/ https://www.ncbi.nlm.nih.gov/pubmed/37568754 http://dx.doi.org/10.3390/cancers15153938 |