Clinical Impact of Polygenic Risk Score for Breast Cancer Risk Prediction in 382 Individuals with Hereditary Breast and Ovarian Cancer Syndrome

SIMPLE SUMMARY: Breast cancer (BC) is the major cause of cancer-related deaths in women worldwide. In addition to genetic diagnostics for variants in high-risk genes, there is a need for better risk stratification to target high-risk individuals. The polygenic risk score (PRS) has emerged as a valua...

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Detalles Bibliográficos
Autores principales: Stiller, Sarah, Drukewitz, Stephan, Lehmann, Kathleen, Hentschel, Julia, Strehlow, Vincent
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10417109/
https://www.ncbi.nlm.nih.gov/pubmed/37568754
http://dx.doi.org/10.3390/cancers15153938

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