Extracellular Matrix Collagen I Differentially Regulates the Metabolic Plasticity of Pancreatic Ductal Adenocarcinoma Parenchymal Cell and Cancer Stem Cell

SIMPLE SUMMARY: Pancreatic ductal adenocarcinoma (PDAC) has an extremely poor prognosis largely due to the intense fibrotic desmoplastic reaction, characterized by high levels of extracellular matrix (ECM) collagen I that constitutes a niche for the cancer stem cells (CSCs). The role of the ECM comp...

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Detalles Bibliográficos
Autores principales: Tavares-Valente, Diana, Cannone, Stefania, Greco, Maria Raffaella, Carvalho, Tiago Miguel Amaral, Baltazar, Fátima, Queirós, Odília, Agrimi, Gennaro, Reshkin, Stephan J., Cardone, Rosa Angela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10417137/
https://www.ncbi.nlm.nih.gov/pubmed/37568684
http://dx.doi.org/10.3390/cancers15153868

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10417137/
https://www.ncbi.nlm.nih.gov/pubmed/37568684
http://dx.doi.org/10.3390/cancers15153868

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