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Extracellular Matrix Collagen I Differentially Regulates the Metabolic Plasticity of Pancreatic Ductal Adenocarcinoma Parenchymal Cell and Cancer Stem Cell
SIMPLE SUMMARY: Pancreatic ductal adenocarcinoma (PDAC) has an extremely poor prognosis largely due to the intense fibrotic desmoplastic reaction, characterized by high levels of extracellular matrix (ECM) collagen I that constitutes a niche for the cancer stem cells (CSCs). The role of the ECM comp...
Autores principales: | Tavares-Valente, Diana, Cannone, Stefania, Greco, Maria Raffaella, Carvalho, Tiago Miguel Amaral, Baltazar, Fátima, Queirós, Odília, Agrimi, Gennaro, Reshkin, Stephan J., Cardone, Rosa Angela |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10417137/ https://www.ncbi.nlm.nih.gov/pubmed/37568684 http://dx.doi.org/10.3390/cancers15153868 |
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