DCUN1D1 Is an Essential Regulator of Prostate Cancer Proliferation and Tumour Growth That Acts through Neddylation of Cullin 1, 3, 4A and 5 and Deregulation of Wnt/Catenin Pathway

Defective in cullin neddylation 1 domain containing 1 (DCUN1D1) is an E3 ligase for the neddylation, a post-translational process similar to and occurring in parallel to ubiquitin proteasome pathway. Although established as an oncogene in a variety of squamous cell carcinomas, the precise role of DC...

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Detalles Bibliográficos
Autores principales: Vava, Akhona, Paccez, Juliano D., Wang, Yihong, Gu, Xuesong, Bhasin, Manoj K., Myers, Michael, Soares, Nelson C., Libermann, Towia A., Zerbini, Luiz F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10417424/
https://www.ncbi.nlm.nih.gov/pubmed/37566052
http://dx.doi.org/10.3390/cells12151973

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10417424/
https://www.ncbi.nlm.nih.gov/pubmed/37566052
http://dx.doi.org/10.3390/cells12151973

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