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Nasal Cytology Changes in Head and Neck Cancer Treatment: A Systemic Review

Nasal cytology is a non-invasive, low-cost exam that can help physicians in the diagnosis of allergic and nonallergic rhinitis, discriminating between different nasal disorders. The aim of this review is to summarize and analyze the current knowledge about nasal cytological examination in head and n...

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Autores principales: Riva, Giuseppe, Urbanelli, Anastasia, Trossarello, Marta, Piazza, Federica, Pecorari, Giancarlo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10417495/
https://www.ncbi.nlm.nih.gov/pubmed/37568843
http://dx.doi.org/10.3390/diagnostics13152480
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author Riva, Giuseppe
Urbanelli, Anastasia
Trossarello, Marta
Piazza, Federica
Pecorari, Giancarlo
author_facet Riva, Giuseppe
Urbanelli, Anastasia
Trossarello, Marta
Piazza, Federica
Pecorari, Giancarlo
author_sort Riva, Giuseppe
collection PubMed
description Nasal cytology is a non-invasive, low-cost exam that can help physicians in the diagnosis of allergic and nonallergic rhinitis, discriminating between different nasal disorders. The aim of this review is to summarize and analyze the current knowledge about nasal cytological examination in head and neck cancer, with a specific focus on the effects of different treatments. Indeed, nasal cytology is important to choose the best treatment for nasal complaints in each patient. A review of the English literature (PubMed, Scopus, Cochrane) was performed (5404 records screened). The inclusion criteria were clinical trials, cohort studies, case–control studies, case series, and case reports regarding nasal cytology in head and neck cancer treatment. Exclusion criteria were as follows: non-human studies, non-English literature, non-cytological evaluations. Two independent reviewers, working separately, extracted the data from all the eligible studies, which were subsequently cross-checked. Five studies were included in qualitative synthesis: three assessed mucosal disorders after radiation therapy and two after total laryngectomy. Radiotherapy can determine mucous or squamous cell metaplasia and neutrophil inflammation. Laryngectomees show hyperplasia of the basal zone cells and mucous cell metaplasia, and they do not develop inflammatory changes. The main limitation of this review is the low number and heterogeneity of studies present in the literature. In conclusion, nasal cytology is useful and allows for identifying mucosal disorders of the nasal cavities after surgery and/or radiotherapy for head and neck cancer. This can help physicians to better treat the nasal complaints of such patients.
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spelling pubmed-104174952023-08-12 Nasal Cytology Changes in Head and Neck Cancer Treatment: A Systemic Review Riva, Giuseppe Urbanelli, Anastasia Trossarello, Marta Piazza, Federica Pecorari, Giancarlo Diagnostics (Basel) Systematic Review Nasal cytology is a non-invasive, low-cost exam that can help physicians in the diagnosis of allergic and nonallergic rhinitis, discriminating between different nasal disorders. The aim of this review is to summarize and analyze the current knowledge about nasal cytological examination in head and neck cancer, with a specific focus on the effects of different treatments. Indeed, nasal cytology is important to choose the best treatment for nasal complaints in each patient. A review of the English literature (PubMed, Scopus, Cochrane) was performed (5404 records screened). The inclusion criteria were clinical trials, cohort studies, case–control studies, case series, and case reports regarding nasal cytology in head and neck cancer treatment. Exclusion criteria were as follows: non-human studies, non-English literature, non-cytological evaluations. Two independent reviewers, working separately, extracted the data from all the eligible studies, which were subsequently cross-checked. Five studies were included in qualitative synthesis: three assessed mucosal disorders after radiation therapy and two after total laryngectomy. Radiotherapy can determine mucous or squamous cell metaplasia and neutrophil inflammation. Laryngectomees show hyperplasia of the basal zone cells and mucous cell metaplasia, and they do not develop inflammatory changes. The main limitation of this review is the low number and heterogeneity of studies present in the literature. In conclusion, nasal cytology is useful and allows for identifying mucosal disorders of the nasal cavities after surgery and/or radiotherapy for head and neck cancer. This can help physicians to better treat the nasal complaints of such patients. MDPI 2023-07-26 /pmc/articles/PMC10417495/ /pubmed/37568843 http://dx.doi.org/10.3390/diagnostics13152480 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Systematic Review
Riva, Giuseppe
Urbanelli, Anastasia
Trossarello, Marta
Piazza, Federica
Pecorari, Giancarlo
Nasal Cytology Changes in Head and Neck Cancer Treatment: A Systemic Review
title Nasal Cytology Changes in Head and Neck Cancer Treatment: A Systemic Review
title_full Nasal Cytology Changes in Head and Neck Cancer Treatment: A Systemic Review
title_fullStr Nasal Cytology Changes in Head and Neck Cancer Treatment: A Systemic Review
title_full_unstemmed Nasal Cytology Changes in Head and Neck Cancer Treatment: A Systemic Review
title_short Nasal Cytology Changes in Head and Neck Cancer Treatment: A Systemic Review
title_sort nasal cytology changes in head and neck cancer treatment: a systemic review
topic Systematic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10417495/
https://www.ncbi.nlm.nih.gov/pubmed/37568843
http://dx.doi.org/10.3390/diagnostics13152480
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