Deep brain stimulation of the medial forebrain bundle - effects on suicidality in treatment-refractory MDD patients?

ABSTRACT: Deep brain stimulation (DBS) of brain circuits involved in mood regulation is a novel tool that is being investigated as a potential treatment for some of the most severe patients with mood disorders. At UTHealth Houston, we have had an ongoing clinical trial with DBS of the medial forebra...

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Detalles Bibliográficos
Autor principal: Soares, J. C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cambridge University Press 2023
Materias:
Abstract
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10417596/
http://dx.doi.org/10.1192/j.eurpsy.2023.145
Descripción
Sumario:ABSTRACT: Deep brain stimulation (DBS) of brain circuits involved in mood regulation is a novel tool that is being investigated as a potential treatment for some of the most severe patients with mood disorders. At UTHealth Houston, we have had an ongoing clinical trial with DBS of the medial forebrain bundle (MFB). Our preliminary results suggest effects in alleviating depressive symptoms in this very severe, refractory patient group. In this presentation, we will review our latest findings, and will also discuss the potential effects of the MFB stimulation on measures of suicidality in this patient population. DISCLOSURE OF INTEREST: None Declared

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