Deep brain stimulation of the medial forebrain bundle - effects on suicidality in treatment-refractory MDD patients?

ABSTRACT: Deep brain stimulation (DBS) of brain circuits involved in mood regulation is a novel tool that is being investigated as a potential treatment for some of the most severe patients with mood disorders. At UTHealth Houston, we have had an ongoing clinical trial with DBS of the medial forebra...

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Autor principal: Soares, J. C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cambridge University Press 2023
Materias:
Abstract
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10417596/
http://dx.doi.org/10.1192/j.eurpsy.2023.145
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author Soares, J. C.
author_facet Soares, J. C.
author_sort Soares, J. C.
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description ABSTRACT: Deep brain stimulation (DBS) of brain circuits involved in mood regulation is a novel tool that is being investigated as a potential treatment for some of the most severe patients with mood disorders. At UTHealth Houston, we have had an ongoing clinical trial with DBS of the medial forebrain bundle (MFB). Our preliminary results suggest effects in alleviating depressive symptoms in this very severe, refractory patient group. In this presentation, we will review our latest findings, and will also discuss the potential effects of the MFB stimulation on measures of suicidality in this patient population. DISCLOSURE OF INTEREST: None Declared
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spelling pubmed-104175962023-08-12 Deep brain stimulation of the medial forebrain bundle - effects on suicidality in treatment-refractory MDD patients? Soares, J. C. Eur Psychiatry Abstract ABSTRACT: Deep brain stimulation (DBS) of brain circuits involved in mood regulation is a novel tool that is being investigated as a potential treatment for some of the most severe patients with mood disorders. At UTHealth Houston, we have had an ongoing clinical trial with DBS of the medial forebrain bundle (MFB). Our preliminary results suggest effects in alleviating depressive symptoms in this very severe, refractory patient group. In this presentation, we will review our latest findings, and will also discuss the potential effects of the MFB stimulation on measures of suicidality in this patient population. DISCLOSURE OF INTEREST: None Declared Cambridge University Press 2023-07-19 /pmc/articles/PMC10417596/ http://dx.doi.org/10.1192/j.eurpsy.2023.145 Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/This is an Open Access article, distributed under the terms of the Creative Commons Attribution licence (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted re-use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Abstract
Soares, J. C.
Deep brain stimulation of the medial forebrain bundle - effects on suicidality in treatment-refractory MDD patients?
title Deep brain stimulation of the medial forebrain bundle - effects on suicidality in treatment-refractory MDD patients?
title_full Deep brain stimulation of the medial forebrain bundle - effects on suicidality in treatment-refractory MDD patients?
title_fullStr Deep brain stimulation of the medial forebrain bundle - effects on suicidality in treatment-refractory MDD patients?
title_full_unstemmed Deep brain stimulation of the medial forebrain bundle - effects on suicidality in treatment-refractory MDD patients?
title_short Deep brain stimulation of the medial forebrain bundle - effects on suicidality in treatment-refractory MDD patients?
title_sort deep brain stimulation of the medial forebrain bundle - effects on suicidality in treatment-refractory mdd patients?
topic Abstract
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10417596/
http://dx.doi.org/10.1192/j.eurpsy.2023.145
work_keys_str_mv AT soaresjc deepbrainstimulationofthemedialforebrainbundleeffectsonsuicidalityintreatmentrefractorymddpatients

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