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Cutaneous Metastasis of Endometrial Cancer and Long-Term Survival: A Scoping Review and Our Experience

Background and Objectives: Cutaneous and soft tissue metastases of endometrial cancer are rare. This review aims to examine the prevalence of cutaneous metastasis, the diagnosis and treatment options, and the impact of cutaneous metastasis of endometrial cancer on overall survival. We also present a...

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Autores principales: Nienhaus, Alexandra, Rajakulendran, Rahavie, Bernad, Elena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10417626/
https://www.ncbi.nlm.nih.gov/pubmed/37568966
http://dx.doi.org/10.3390/diagnostics13152603
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author Nienhaus, Alexandra
Rajakulendran, Rahavie
Bernad, Elena
author_facet Nienhaus, Alexandra
Rajakulendran, Rahavie
Bernad, Elena
author_sort Nienhaus, Alexandra
collection PubMed
description Background and Objectives: Cutaneous and soft tissue metastases of endometrial cancer are rare. This review aims to examine the prevalence of cutaneous metastasis, the diagnosis and treatment options, and the impact of cutaneous metastasis of endometrial cancer on overall survival. We also present a particular case with a long-term overall survival. Materials and Methods: A systematic literature search was conducted on PubMed and PubMed Central using the following keywords: endometrial carcinoma metastasis, cutaneous metastasis, and five-year overall survival. Results: We identified 326 results and checked their titles for eligibility. There were eight studies included. We also presented a case of a 51-year-old woman with cutaneous metastasis and a large soft tissue metastasis with a prolonged overall survival of about 13 years after the appearance of the first cutaneous metastasis. Conclusions: This paper highlights the importance of skin evaluations in patients diagnosed with endometrial cancer. Healthcare providers must consider the possibility of cutaneous metastasis localization in patients with endometrial cancer to assign the correct stage and apply the appropriate treatment to increase long-term survival.
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spelling pubmed-104176262023-08-12 Cutaneous Metastasis of Endometrial Cancer and Long-Term Survival: A Scoping Review and Our Experience Nienhaus, Alexandra Rajakulendran, Rahavie Bernad, Elena Diagnostics (Basel) Review Background and Objectives: Cutaneous and soft tissue metastases of endometrial cancer are rare. This review aims to examine the prevalence of cutaneous metastasis, the diagnosis and treatment options, and the impact of cutaneous metastasis of endometrial cancer on overall survival. We also present a particular case with a long-term overall survival. Materials and Methods: A systematic literature search was conducted on PubMed and PubMed Central using the following keywords: endometrial carcinoma metastasis, cutaneous metastasis, and five-year overall survival. Results: We identified 326 results and checked their titles for eligibility. There were eight studies included. We also presented a case of a 51-year-old woman with cutaneous metastasis and a large soft tissue metastasis with a prolonged overall survival of about 13 years after the appearance of the first cutaneous metastasis. Conclusions: This paper highlights the importance of skin evaluations in patients diagnosed with endometrial cancer. Healthcare providers must consider the possibility of cutaneous metastasis localization in patients with endometrial cancer to assign the correct stage and apply the appropriate treatment to increase long-term survival. MDPI 2023-08-04 /pmc/articles/PMC10417626/ /pubmed/37568966 http://dx.doi.org/10.3390/diagnostics13152603 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Nienhaus, Alexandra
Rajakulendran, Rahavie
Bernad, Elena
Cutaneous Metastasis of Endometrial Cancer and Long-Term Survival: A Scoping Review and Our Experience
title Cutaneous Metastasis of Endometrial Cancer and Long-Term Survival: A Scoping Review and Our Experience
title_full Cutaneous Metastasis of Endometrial Cancer and Long-Term Survival: A Scoping Review and Our Experience
title_fullStr Cutaneous Metastasis of Endometrial Cancer and Long-Term Survival: A Scoping Review and Our Experience
title_full_unstemmed Cutaneous Metastasis of Endometrial Cancer and Long-Term Survival: A Scoping Review and Our Experience
title_short Cutaneous Metastasis of Endometrial Cancer and Long-Term Survival: A Scoping Review and Our Experience
title_sort cutaneous metastasis of endometrial cancer and long-term survival: a scoping review and our experience
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10417626/
https://www.ncbi.nlm.nih.gov/pubmed/37568966
http://dx.doi.org/10.3390/diagnostics13152603
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