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YY1 Knockdown Relieves the Differentiation Block and Restores Apoptosis in AML Cells

SIMPLE SUMMARY: Acute myeloid leukemia (AML) is characterized by the expansion of clonally derived hematopoietic precursors undergoing a partial or complete maturation block. De novo AML is characterized by recurrent cytogenetic alterations such as chromosomal translocations. However, in the recent...

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Detalles Bibliográficos
Autores principales: Noguera, Nelida Ines, Travaglini, Serena, Scalea, Stefania, Catalanotto, Caterina, Reale, Anna, Zampieri, Michele, Zaza, Alessandra, Ricciardi, Maria Rosaria, Angelini, Daniela Francesca, Tafuri, Agostino, Ottone, Tiziana, Voso, Maria Teresa, Zardo, Giuseppe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10417667/
https://www.ncbi.nlm.nih.gov/pubmed/37568827
http://dx.doi.org/10.3390/cancers15154010

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