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Correlation between [(68)Ga]Ga-FAPI-46 PET Imaging and HIF-1α Immunohistochemical Analysis in Cervical Cancer: Proof-of-Concept

SIMPLE SUMMARY: Hypoxia is a phenomenon common in cervical cancer. Both the presence and function of CAFs are upregulated in a hypoxic environment. A key factor in the physiological response to hypoxia is hypoxia-inducible factor-1alpha (HIF-1 [Formula: see text]). We hypothesized that [(68)Ga]Ga-FA...

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Detalles Bibliográficos
Autores principales: Mokoala, Kgomotso M. G., Lawal, Ismaheel O., Maserumule, Letjie C., Bida, Meshack, Maes, Alex, Ndlovu, Honest, Reed, Janet, Mahapane, Johncy, Davis, Cindy, Van de Wiele, Christophe, Popoola, Gbenga, Giesel, Frederik L., Vorster, Mariza, Sathekge, Mike M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10417683/
https://www.ncbi.nlm.nih.gov/pubmed/37568769
http://dx.doi.org/10.3390/cancers15153953