Knock Out of CGN and CGNL1 in MDCK Cells Affects Claudin-2 but Has a Minor Impact on Tight Junction Barrier Function

Cingulin (CGN) and paracingulin (CGNL1) are cytoplasmic proteins of tight junctions (TJs), where they play a role in tethering ZO-1 to the actomyosin and microtubule cytoskeletons. The role of CGN and CGNL1 in the barrier function of epithelia is not completely understood. Here, we analyzed the effe...

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Detalles Bibliográficos
Autores principales: Maupérin, Marine, Sassi, Ali, Méan, Isabelle, Feraille, Eric, Citi, Sandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10417749/
https://www.ncbi.nlm.nih.gov/pubmed/37566083
http://dx.doi.org/10.3390/cells12152004

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10417749/
https://www.ncbi.nlm.nih.gov/pubmed/37566083
http://dx.doi.org/10.3390/cells12152004

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