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Model-based compound hypothesis testing for snATAC-seq data with PACS

Single nucleus ATAC-seq (snATAC-seq) experimental designs have become increasingly complex with multiple factors that might affect chromatin accessibility, including cell type, tissue of origin, sample location, batch, etc., whose compound effects are difficult to test by existing methods. In additi...

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Detalles Bibliográficos
Autores principales: Miao, Zhen, Wang, Jianqiao, Park, Kernyu, Kuang, Da, Kim, Junhyong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10418058/
https://www.ncbi.nlm.nih.gov/pubmed/37577623
http://dx.doi.org/10.1101/2023.07.30.551108