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DePARylation is critical for S phase progression and cell survival

Poly(ADP-ribose)ylation or PARylation by PAR polymerase 1 (PARP1) and dePARylation by poly(ADP-ribose) glycohydrolase (PARG) are equally important for the dynamic regulation of DNA damage response. PARG, the most active dePARylation enzyme, is recruited to sites of DNA damage via pADPr-dependent and...

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Detalles Bibliográficos
Autores principales: Nie, Litong, Wang, Chao, Huang, Min, Liu, Xiaoguang, Feng, Xu, Tang, Mengfan, Li, Siting, Hang, Qinglei, Teng, Hongqi, Shen, Xi, Ma, Li, Gan, Boyi, Chen, Junjie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10418084/
https://www.ncbi.nlm.nih.gov/pubmed/37577639
http://dx.doi.org/10.1101/2023.07.31.551317