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Extrachromosomal Telomeres Derived from Excessive Strand Displacements
Alternative Lengthening of Telomeres (ALT) is a telomere maintenance mechanism mediated by break-induced replication (BIR), evident in approximately 15% of human cancers. A characteristic feature of ALT cancers is the presence of C-circles, circular single-stranded telomeric DNAs composed of C-rich...
Autores principales: | Lee, Junyeop, Lee, Jina, Sohn, Eric J., Taglialatela, Angelo, O’Sullivan, Roderick J., Ciccia, Alberto, Min, Jaewon |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10418088/ https://www.ncbi.nlm.nih.gov/pubmed/37577643 http://dx.doi.org/10.1101/2023.07.31.551186 |
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