Cargando…
Sensitization of meningeal afferents to locomotion-related meningeal deformations in a migraine model
Migraine headache is hypothesized to involve the activation and sensitization of trigeminal sensory afferents that innervate the cranial meninges. To better understand migraine pathophysiology and improve clinical translation, we used two-photon calcium imaging via a closed cranial window in awake m...
Autores principales: | Blaeser, Andrew S, Zhao, Jun, Sugden, Arthur U, Carneiro-Nascimento, Simone, Andermann, Mark L, Levy, Dan |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10418100/ https://www.ncbi.nlm.nih.gov/pubmed/37577675 http://dx.doi.org/10.1101/2023.07.31.549838 |
Ejemplares similares
-
Trigeminal afferents sense locomotion-related meningeal deformations
por: Blaeser, Andrew S., et al.
Publicado: (2022) -
Cortical Spreading Depression Promotes Persistent Mechanical Sensitization of Intracranial Meningeal Afferents: Implications for the Intracranial Mechanosensitivity of Migraine
por: Zhao, Jun, et al.
Publicado: (2016) -
Cortical spreading depression and meningeal nociception
por: Carneiro-Nascimento, Simone, et al.
Publicado: (2022) -
The CGRP receptor antagonist BIBN4096 inhibits prolonged meningeal afferent activation evoked by brief local K(+) stimulation but not cortical spreading depression-induced afferent sensitization
por: Zhao, Jun, et al.
Publicado: (2017) -
Sensitization of dural afferents underlies migraine-related behavior following meningeal application of interleukin-6 (IL-6)
por: Yan, Jin, et al.
Publicado: (2012)