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Niclosamide potentiates TMEM16A and induces vasoconstriction

The TMEM16A calcium-activated chloride channel is a promising therapeutic target for various diseases. Niclosamide, an anthelmintic medication, has been considered as a TMEM16A inhibitor for treating asthma and chronic obstructive pulmonary disease, but was recently found to possess broad-spectrum o...

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Detalles Bibliográficos
Autores principales:	Liang, Pengfei, Wan, Yui Chun S., Yu, Kuai, Hartzell, H. Criss, Yang, Huanghe
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cold Spring Harbor Laboratory 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10418162/ https://www.ncbi.nlm.nih.gov/pubmed/37577682 http://dx.doi.org/10.1101/2023.07.31.551400

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