Cargando…

Chaperone-assisted cryo-EM structure of P. aeruginosa PhuR reveals molecular basis for heme uptake

Pathogenic bacteria, such as Pseudomonas aeruginosa, depend on scavenging heme for the acquisition of iron, an essential nutrient. The TonB-dependent transporter (TBDT) PhuR is the major heme uptake protein in P. aeruginosa clinical isolates. However, a comprehensive understanding of heme recognitio...

Descripción completa

Detalles Bibliográficos
Autores principales:	Knejski, Paweł P., Erramilli, Satchal K., Kossiakoff, Anthony A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cold Spring Harbor Laboratory 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10418163/ https://www.ncbi.nlm.nih.gov/pubmed/37577460 http://dx.doi.org/10.1101/2023.08.01.551527

Ejemplares similares

A peroxisomal ubiquitin ligase complex forms a retrotranslocation channel
por: Feng, Peiqiang, et al.
Publicado: (2022)

Function Coupling Mechanism of PhuS and HemO in Heme Degradation
por: Lee, Michael J. Y., et al.
Publicado: (2017)

Synthetic antibodies against BRIL as universal fiducial marks for single−particle cryoEM structure determination of membrane proteins
por: Mukherjee, Somnath, et al.
Publicado: (2020)

Cryo-EM of CcsBA reveals the basis for cytochrome c biogenesis and heme transport
por: Mendez, Deanna L., et al.
Publicado: (2021)

Cryo-EM structure of the diapause chaperone artemin
por: Parvate, Amar D., et al.
Publicado: (2022)

The heme-binding protein PhuS transcriptionally regulates the Pseudomonas aeruginosa tandem sRNA prrF1,F2 locus
por: Wilson, Tyree, et al.
Publicado: (2021)

Development, structure, and mechanism of synthetic antibodies that target claudin and Clostridium perfringens enterotoxin complexes
por: Orlando, Benjamin J., et al.
Publicado: (2022)

Cryo-EM structures of a prokaryotic heme transporter CydDC
por: Zhu, Chen, et al.
Publicado: (2023)

El relojero de Dien Bien Phu
Publicado: (1975)

Structure of human Frizzled5 by fiducial-assisted cryo-EM supports a heterodimeric mechanism of canonical Wnt signaling
por: Tsutsumi, Naotaka, et al.
Publicado: (2020)

Elucidating the structural basis for differing enzyme inhibitor potency by cryo-EM
por: Rawson, Shaun, et al.
Publicado: (2018)

Cryo-EM reveals the structural basis of microtubule depolymerization by kinesin-13s
por: Benoit, Matthieu P.M.H., et al.
Publicado: (2018)

Cryo-EM reveals the molecular basis of laminin polymerization and LN-lamininopathies
por: Kulczyk, Arkadiusz W., et al.
Publicado: (2023)

Cryo-EM structures of staphylococcal IsdB bound to human hemoglobin reveal the process of heme extraction
por: De Bei, Omar, et al.
Publicado: (2022)

Helminth infections in dogs in Phu Tho Province, northern Vietnam
por: Nguyen, Thi Thuy Man, et al.
Publicado: (2022)

Isoform- and ligand-specific modulation of the adhesion GPCR ADGRL3/Latrophilin3 by a synthetic binder
por: Kordon, Szymon P., et al.
Publicado: (2023)

Author Correction: Cryo-EM reveals the structural basis of microtubule depolymerization by kinesin-13s
por: Benoit, Matthieu P. M. H., et al.
Publicado: (2018)

Cryo-EM structure of the RuvAB-Holliday junction intermediate complex from Pseudomonas aeruginosa
por: Zhang, Xu, et al.
Publicado: (2023)

A snapshot of cryo‐EM
por: Skiniotis, Georgios
Publicado: (2016)

Interpreting the cryo-EM map
por: Rosenthal, Peter B.
Publicado: (2019)

COVID-19 and cryo-EM
por: Subramaniam, Sriram
Publicado: (2020)

Cryo-EM at ACA 2022
por: Subramaniam, Sriram, et al.
Publicado: (2022)

Marine algal species and their distribution in Phu Quoc marine protected area
por: Van Tien, Huynh, et al.
Publicado: (2019)

Tools for the cryo-EM gold rush: going from the cryo-EM map to the atomistic model
por: Kim, Doo Nam, et al.
Publicado: (2017)

Human Taeniasis and Cysticercosis and Related Factors in Phu Tho Province, Northern Vietnam
por: Binh, Vu Thi Lam, et al.
Publicado: (2021)

Reliable cryo-EM resolution estimation with modified Fourier shell correlation
por: Penczek, Pawel A.
Publicado: (2020)

Exploring applications of crowdsourcing to cryo-EM
por: Bruggemann, Jacob, et al.
Publicado: (2018)

Cryo-EM Structure of the Exocyst Complex
por: Mei, Kunrong, et al.
Publicado: (2018)

Density modification of cryo-EM maps
por: Terwilliger, Thomas C., et al.
Publicado: (2020)

Fast multiscale reconstruction for Cryo-EM()
por: Donati, Laurène, et al.
Publicado: (2018)

Cryo‐EM targets in CASP14
por: Cragnolini, Tristan, et al.
Publicado: (2021)

Cryo-EM structure of the SEA complex
por: Tafur, Lucas, et al.
Publicado: (2022)

Cryo‐EM structures of coagulation factors
por: Di Cera, Enrico, et al.
Publicado: (2022)

AlphaFold2 and CryoEM: Revisiting CryoEM modeling in near-atomic resolution density maps
por: Hryc, Corey F., et al.
Publicado: (2022)

Detergents and alternatives in cryo-EM studies of membrane proteins: Detergents and alternatives in cryo-EM studies of membrane proteins
por: Li, Shuo
Publicado: (2022)

Structural basis for tetraspanin functions as revealed by the cryo-EM structure of uroplakin complexes at 6-Å resolution
por: Min, Guangwei, et al.
Publicado: (2006)

Cryo-EM Structure of a Relaxase Reveals the Molecular Basis of DNA Unwinding during Bacterial Conjugation
por: Ilangovan, Aravindan, et al.
Publicado: (2017)

Structural basis for the inhibition of HTLV-1 integration inferred from cryo-EM deltaretroviral intasome structures
por: Barski, Michal S., et al.
Publicado: (2021)

Cryo-EM structures show the mechanistic basis of pan-peptidase inhibition by human α(2)-macroglobulin
por: Luque, Daniel, et al.
Publicado: (2022)

‘Cryo-EM’: electron cryomicroscopy, cryo electron microscopy or something else?
por: Henderson, Richard, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_aqibcr3mjetuvm9qv8v93kjbcn