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Mosquito midgut stem cell cellular defense response limits Plasmodium parasite infection

A novel cellular response of midgut progenitors (stem cells and enteroblasts) to Plasmodium berghei infection was investigated in Anopheles stephensi. The presence of developing oocysts triggers proliferation of midgut progenitors that is modulated by the Jak/STAT pathway, and proportional to the nu...

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Detalles Bibliográficos
Autores principales: Barletta, Ana-Beatriz F., Smith, Jamie C., Burkart, Emily, Bondarenko, Simon, Sharakhov, Igor, Criscione, Frank, O’Brochta, David, Barillas-Mury, Carolina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10418181/
https://www.ncbi.nlm.nih.gov/pubmed/37577486
http://dx.doi.org/10.1101/2023.08.02.551669