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SpaRx: Elucidate single-cell spatial heterogeneity of drug responses for personalized treatment
Spatial cellular heterogeneity contributes to differential drug responses in a tumor lesion and potential therapeutic resistance. Recent emerging spatial technologies such as CosMx SMI, MERSCOPE, and Xenium delineate the spatial gene expression patterns at the single cell resolution. This provides u...
Autores principales: | Tang, Ziyang, Liu, Xiang, Li, Zuotian, Zhang, Tonglin, Yang, Baijian, Su, Jing, Song, Qianqian |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10418183/ https://www.ncbi.nlm.nih.gov/pubmed/37577665 http://dx.doi.org/10.1101/2023.08.03.551911 |
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