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SpaRx: Elucidate single-cell spatial heterogeneity of drug responses for personalized treatment

Spatial cellular heterogeneity contributes to differential drug responses in a tumor lesion and potential therapeutic resistance. Recent emerging spatial technologies such as CosMx SMI, MERSCOPE, and Xenium delineate the spatial gene expression patterns at the single cell resolution. This provides u...

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Detalles Bibliográficos
Autores principales: Tang, Ziyang, Liu, Xiang, Li, Zuotian, Zhang, Tonglin, Yang, Baijian, Su, Jing, Song, Qianqian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10418183/
https://www.ncbi.nlm.nih.gov/pubmed/37577665
http://dx.doi.org/10.1101/2023.08.03.551911