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Tmem263 deletion disrupts the GH/IGF-1 axis and causes dwarfism and impairs skeletal acquisition

Genome-wide association studies (GWAS) have identified a large number of candidate genes believed to affect longitudinal bone growth and bone mass. One of these candidate genes, TMEM263, encodes a poorly characterized plasma membrane protein. Single nucleotide polymorphisms in TMEM263 are associated...

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Detalles Bibliográficos
Autores principales:	Sarver, Dylan C., Garcia-Diaz, Jean, Saqib, Muzna, Riddle, Ryan C., Wong, G. William
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cold Spring Harbor Laboratory 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10418210/ https://www.ncbi.nlm.nih.gov/pubmed/37577461 http://dx.doi.org/10.1101/2023.08.02.551694

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