A force-sensitive mutation reveals a spindle assembly checkpoint-independent role for dynein in anaphase progression

The cytoplasmic dynein-1 (dynein) motor organizes cells by shaping microtubule networks and moving a large variety of cargoes along them. However, dynein’s diverse roles complicate in vivo studies of its functions significantly. To address this issue, we have used gene editing to generate a series o...

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Detalles Bibliográficos
Autores principales: Salvador-Garcia, David, Jin, Li, Hensley, Andrew, Gölcük, Mert, Gallaud, Emmanuel, Chaaban, Sami, Port, Fillip, Vagnoni, Alessio, Planelles-Herrero, Vicente José, McClintock, Mark A., Derivery, Emmanuel, Carter, Andrew P., Giet, Régis, Gür, Mert, Yildiz, Ahmet, Bullock, Simon L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10418259/
https://www.ncbi.nlm.nih.gov/pubmed/37577480
http://dx.doi.org/10.1101/2023.08.03.551815

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