Fucosylated glycoproteins and fucosylated glycolipids play opposing roles in cholera intoxication

Cholera toxin (CT) is the etiological agent of cholera. Here we report that multiple classes of fucosylated glycoconjugates function in CT binding and intoxication of intestinal epithelial cells. In Colo205 cells, knockout of B3GNT5, the enzyme required for synthesis of lacto- and neolacto-series gl...

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Detalles Bibliográficos
Autores principales: Ghorashi, Atossa C., Boucher, Andrew, Archer-Hartmann, Stephanie A., Murray, Nathan B., Konada, Rohit Sai Reddy, Zhang, Xunzhi, Xing, Chao, Azadi, Parastoo, Yrlid, Ulf, Kohler, Jennifer J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10418270/
https://www.ncbi.nlm.nih.gov/pubmed/37577488
http://dx.doi.org/10.1101/2023.08.02.551727

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