A Functional Pipeline of Genome-Wide Association Data Leads to Midostaurin as a Repurposed Drug for Alzheimer’s Disease

Genome-wide association studies (GWAS) constitute a powerful tool to identify the different biochemical pathways associated with disease. This knowledge can be used to prioritize drugs targeting these routes, paving the road to clinical application. Here, we describe DAGGER (Drug Repositioning by An...

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Detalles Bibliográficos
Autores principales: Esteban-Martos, Alvaro, Brokate-Llanos, Ana Maria, Real, Luis Miguel, Melgar-Locatelli, Sonia, de Rojas, Itziar, Castro-Zavala, Adriana, Bravo, Maria Jose, Mañas-Padilla, Maria del Carmen, García-González, Pablo, Ruiz-Galdon, Maximiliano, Pacheco-Sánchez, Beatriz, Polvillo, Rocío, Rodriguez de Fonseca, Fernando, González, Irene, Castilla-Ortega, Estela, Muñoz, Manuel J., Rivera, Patricia, Reyes-Engel, Armando, Ruiz, Agustin, Royo, Jose Luis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10418421/
https://www.ncbi.nlm.nih.gov/pubmed/37569459
http://dx.doi.org/10.3390/ijms241512079

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10418421/
https://www.ncbi.nlm.nih.gov/pubmed/37569459
http://dx.doi.org/10.3390/ijms241512079

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