Retinoic Acid Receptor β Loss in Hepatocytes Increases Steatosis and Elevates the Integrated Stress Response in Alcohol-Associated Liver Disease

In alcohol-associated liver disease (ALD), hepatic reductions in vitamin A and perturbations in vitamin A metabolism are common. However, the roles that the vitamin A receptors, termed retinoic acid receptors (RARs), may have in preventing the pathophysiology of ALD remains unclear. Our prior data i...

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Detalles Bibliográficos
Autores principales: Melis, Marta, Trasino, Steven E., Tang, Xiao-Han, Rappa, Andrew, Zhang, Tuo, Qin, Lihui, Gudas, Lorraine J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10418449/
https://www.ncbi.nlm.nih.gov/pubmed/37569418
http://dx.doi.org/10.3390/ijms241512035

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