Cargando…

Identification of TRPM2 as a Potential Therapeutic Target Associated with Immune Infiltration: A Comprehensive Pan-Cancer Analysis and Experimental Verification in Ovarian Cancer

The exact role of Transient receptor potential melastatin 2 (TRPM2) in tumor progression and immunomodulation remains elusive. We comprehensively investigated the expression pattern, diagnostic value, prognostic impact, genetic and epigenetic alterations of TRPM2 in pan-cancer. Then, we explored und...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zheng, Danxi, Long, Siyu, Xi, Mingrong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10418504/ https://www.ncbi.nlm.nih.gov/pubmed/37569287 http://dx.doi.org/10.3390/ijms241511912

Ejemplares similares

A comprehensive pan-cancer analysis identifies a novel glycolysis score and its hub genes as prognostic and immunological biomarkers
por: Zheng, Danxi, et al.
Publicado: (2023)

Identification of TRPM2 as a prognostic factor correlated with immune infiltration in ovarian cancer
por: Huang, Wei, et al.
Publicado: (2023)

Comprehensive Pan-Cancer Analysis of TRPM8 in Tumor Metabolism and Immune Escape
por: Zhang, Wei, et al.
Publicado: (2022)

Comprehensive analysis of DTYMK in pan-cancer and verification in lung adenocarcinoma
por: Zhang, Yue, et al.
Publicado: (2022)

Systematic Pan-Cancer Analysis and Experimental Verification Identify FOXA1 as an Immunological and Prognostic Biomarker in Epithelial Ovarian Cancer
por: Wang, Kai, et al.
Publicado: (2022)

Comprehensive Landscape of RRM2 with Immune Infiltration in Pan-Cancer
por: Zhou, Zijian, et al.
Publicado: (2022)

Integrated pan-cancer analysis and experimental verification of the roles of tropomyosin 4 in gastric cancer
por: Guo, Qijing, et al.
Publicado: (2023)

Comprehensive Analysis on Prognosis and Immune Infiltration of Lysyl Oxidase Family Members in Pancreatic Adenocarcinoma With Experimental Verification
por: Jiang, Chao, et al.
Publicado: (2022)

A comprehensive analysis of gasdermin family gene as therapeutic targets in pan-cancer
por: Huo, Cheng-Long, et al.
Publicado: (2022)

Comprehensive analysis of the correlation of the pan-cancer gene HAUS5 with prognosis and immune infiltration in liver cancer
por: Zhang, Wenbing, et al.
Publicado: (2023)

Identification of prognostic biomarkers in the CMTM family genes of human ovarian cancer through bioinformatics analysis and experimental verification
por: Zhang, Mengjun, et al.
Publicado: (2022)

Pan-Cancer Analysis of Prognostic and Immune Infiltrates for CXCs
por: Li, Long, et al.
Publicado: (2021)

Therapeutic potential of TRPM8 antagonists in prostate cancer
por: Di Donato, Marzia, et al.
Publicado: (2021)

Therapeutic potential of TRPM8 channels in cancer treatment
por: Ochoa, Sara V., et al.
Publicado: (2023)

A comprehensive prognostic and immune infiltration analysis of EXOC3L1 in pan-cancer
por: Zhang, Zhan-Fei
Publicado: (2022)

Comprehensive analysis of PILRΑ’s association with the prognosis, tumor immune infiltration, and immunotherapy in pan-cancer
por: Li, Qiao, et al.
Publicado: (2023)

Comprehensive Analysis and Validation of Solute Carrier Family 25 (SLC25) and Its Correlation with Immune Infiltration in Pan-Cancer
por: Liu, Ao-ran, et al.
Publicado: (2022)

Experimental identification of cancer driver alterations in the era of pan‐cancer genomics
por: Korenjak, Michael, et al.
Publicado: (2019)

Comprehensive Pan-Cancer Analysis of Senescence With Cancer Prognosis and Immunotherapy
por: Zhao, Qinfei, et al.
Publicado: (2022)

Oncogenic role of copper‑induced cell death‑associated protein DLD in human cancer: A pan‑cancer analysis and experimental verification
por: Qi, Han, et al.
Publicado: (2023)

Verification of the methodology for evaluating tumor-infiltrating lymphocytes in colorectal cancer
por: Matsutani, Shinji, et al.
Publicado: (2018)

Identification of Prognostic Biomarkers Among FAM83 Family Genes in Human Ovarian Cancer Through Bioinformatic Analysis and Experimental Verification
por: Lin, Shaochong, et al.
Publicado: (2021)

Comprehensive analysis of TLX2 in pan cancer as a prognostic and immunologic biomarker and validation in ovarian cancer
por: Chen, Buze, et al.
Publicado: (2023)

Verification of HE-based CTV in laryngeal and hypopharyngeal cancer using pan-cytokeratin
por: Ligtenberg, Hans, et al.
Publicado: (2018)

Multi-Omics Analysis and Verification of the Oncogenic Value of CCT8 in Pan-Cancers
por: Gong, Lian, et al.
Publicado: (2023)

The Prognostic Value and Immune Infiltration of USP10 in Pan-Cancer: A Potential Therapeutic Target
por: Gao, Dacheng, et al.
Publicado: (2022)

Risk of cervical intraepithelial neoplasia grade 3 or more diagnoses for human papillomavirus16/18-positive women by cytology and co-infection status
por: Ao, Mengyin, et al.
Publicado: (2023)

CEP55 as a Promising Immune Intervention Marker to Regulate Tumor Progression: A Pan-Cancer Analysis with Experimental Verification
por: Wang, Gang, et al.
Publicado: (2023)

Identification and Verification of Biomarkers and Immune Infiltration in Obesity-Related Atrial Fibrillation
por: Xie, Zhonghui, et al.
Publicado: (2023)

Comprehensive analysis of prognostic gene signatures based on immune infiltration of ovarian cancer
por: Yan, Shibai, et al.
Publicado: (2020)

LAMP2 as a Biomarker Related to Prognosis and Immune Infiltration in Esophageal Cancer and Other Cancers: A Comprehensive Pan-Cancer Analysis
por: Liu, Shan-peng, et al.
Publicado: (2022)

Endoplasmic Reticulum Stress-Related Ten-Biomarker Risk Classifier for Survival Evaluation in Epithelial Ovarian Cancer and TRPM2: A Potential Therapeutic Target of Ovarian Cancer
por: Zhang, Minghai, et al.
Publicado: (2023)

Role of TRPM7 in Cancer: Potential as Molecular Biomarker and Therapeutic Target
por: Yee, Nelson S.
Publicado: (2017)

TRPM Family Channels in Cancer
por: Hantute-Ghesquier, Aline, et al.
Publicado: (2018)

Identification and verification of an exosome-related gene risk model to predict prognosis and evaluate immune infiltration for colorectal cancer
por: Shao, Huan, et al.
Publicado: (2023)

Identification and verification of the prognostic value of the glutathione S-transferase Mu genes in gastric cancer
por: Chen, Yeyang, et al.
Publicado: (2020)

The Establishment and Experimental Verification of an lncRNA-Derived CD8+ T Cell Infiltration ceRNA Network in Colorectal Cancer
por: Wu, Qi, et al.
Publicado: (2022)

Identification and Verification of Necroptosis-Related Gene Signature With Prognosis and Tumor Immune Microenvironment in Ovarian Cancer
por: Wang, Zitao, et al.
Publicado: (2022)

MiR-494 Inhibits Epithelial Ovarian Cancer Growth by Targeting c-Myc
por: Yuan, Jialing, et al.
Publicado: (2016)

Identification and verification of immune-related biomarkers and immune infiltration in diabetic heart failure
por: Zhong, Zuoquan, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_39f4p4gt5gn29meaeeanf4k2fg