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Distinct pulmonary and systemic effects of dexamethasone in severe COVID-19

Dexamethasone is the standard of care for critically ill patients with COVID-19, but the mechanisms by which it decreases mortality and its immunological effects in this setting are not understood. We performed bulk and single-cell RNA sequencing of the lower respiratory tract and blood, and plasma...

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Detalles Bibliográficos
Autores principales: Neyton, Lucile P. A., Patel, Ravi K., Sarma, Aartik, Willmore, Andrew, Haller, Sidney C., Kangelaris, Kirsten N., Eckalbar, Walter L., Erle, David J., Krummel, Matthew F., Hendrickson, Carolyn M., Woodruff, Prescott G., Langelier, Charles R., Calfee, Carolyn S., Fragiadakis, Gabriela K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Journal Experts 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10418533/
https://www.ncbi.nlm.nih.gov/pubmed/37577607
http://dx.doi.org/10.21203/rs.3.rs-3168149/v1