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Distinct pulmonary and systemic effects of dexamethasone in severe COVID-19
Dexamethasone is the standard of care for critically ill patients with COVID-19, but the mechanisms by which it decreases mortality and its immunological effects in this setting are not understood. We performed bulk and single-cell RNA sequencing of the lower respiratory tract and blood, and plasma...
Autores principales: | Neyton, Lucile P. A., Patel, Ravi K., Sarma, Aartik, Willmore, Andrew, Haller, Sidney C., Kangelaris, Kirsten N., Eckalbar, Walter L., Erle, David J., Krummel, Matthew F., Hendrickson, Carolyn M., Woodruff, Prescott G., Langelier, Charles R., Calfee, Carolyn S., Fragiadakis, Gabriela K. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Journal Experts
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10418533/ https://www.ncbi.nlm.nih.gov/pubmed/37577607 http://dx.doi.org/10.21203/rs.3.rs-3168149/v1 |
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