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ClusterDE: a post-clustering differential expression (DE) method robust to false-positive inflation caused by double dipping
In typical single-cell RNA-seq (scRNA-seq) data analysis, a clustering algorithm is applied to find putative cell types as clusters, and then a statistical differential expression (DE) test is employed to identify the differentially expressed (DE) genes between the cell clusters. However, this commo...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Journal Experts
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10418557/ https://www.ncbi.nlm.nih.gov/pubmed/37577698 http://dx.doi.org/10.21203/rs.3.rs-3211191/v1 |