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Photodynamic Therapy for Colorectal Cancer: An Update and a Look to the Future
This review provides an update on the current state of photodynamic therapy (PDT) for colorectal cancer (CRC) and explores potential future directions in this field. PDT has emerged as a promising minimally invasive treatment modality that utilizes photosensitizers and specific light wavelengths to...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10418644/ https://www.ncbi.nlm.nih.gov/pubmed/37569580 http://dx.doi.org/10.3390/ijms241512204 |
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author | Rodrigues, José A. Correia, José H. |
author_facet | Rodrigues, José A. Correia, José H. |
author_sort | Rodrigues, José A. |
collection | PubMed |
description | This review provides an update on the current state of photodynamic therapy (PDT) for colorectal cancer (CRC) and explores potential future directions in this field. PDT has emerged as a promising minimally invasive treatment modality that utilizes photosensitizers and specific light wavelengths to induce cell death in targeted tumor tissues. In recent years, significant progress has been made in understanding the underlying mechanisms, optimizing treatment protocols, and improving the efficacy of PDT for CRC. This article highlights key advancements in PDT techniques, including novel photosensitizers, light sources, and delivery methods. Furthermore, it discusses ongoing research efforts and potential future directions, such as combination therapies and nanotechnology-based approaches. By elucidating the current landscape and providing insights into future directions, this review aims to guide researchers and clinicians in harnessing the full potential of PDT for the effective management of CRC. |
format | Online Article Text |
id | pubmed-10418644 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-104186442023-08-12 Photodynamic Therapy for Colorectal Cancer: An Update and a Look to the Future Rodrigues, José A. Correia, José H. Int J Mol Sci Review This review provides an update on the current state of photodynamic therapy (PDT) for colorectal cancer (CRC) and explores potential future directions in this field. PDT has emerged as a promising minimally invasive treatment modality that utilizes photosensitizers and specific light wavelengths to induce cell death in targeted tumor tissues. In recent years, significant progress has been made in understanding the underlying mechanisms, optimizing treatment protocols, and improving the efficacy of PDT for CRC. This article highlights key advancements in PDT techniques, including novel photosensitizers, light sources, and delivery methods. Furthermore, it discusses ongoing research efforts and potential future directions, such as combination therapies and nanotechnology-based approaches. By elucidating the current landscape and providing insights into future directions, this review aims to guide researchers and clinicians in harnessing the full potential of PDT for the effective management of CRC. MDPI 2023-07-30 /pmc/articles/PMC10418644/ /pubmed/37569580 http://dx.doi.org/10.3390/ijms241512204 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Rodrigues, José A. Correia, José H. Photodynamic Therapy for Colorectal Cancer: An Update and a Look to the Future |
title | Photodynamic Therapy for Colorectal Cancer: An Update and a Look to the Future |
title_full | Photodynamic Therapy for Colorectal Cancer: An Update and a Look to the Future |
title_fullStr | Photodynamic Therapy for Colorectal Cancer: An Update and a Look to the Future |
title_full_unstemmed | Photodynamic Therapy for Colorectal Cancer: An Update and a Look to the Future |
title_short | Photodynamic Therapy for Colorectal Cancer: An Update and a Look to the Future |
title_sort | photodynamic therapy for colorectal cancer: an update and a look to the future |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10418644/ https://www.ncbi.nlm.nih.gov/pubmed/37569580 http://dx.doi.org/10.3390/ijms241512204 |
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