Cargando…

Photodynamic Therapy for Colorectal Cancer: An Update and a Look to the Future

This review provides an update on the current state of photodynamic therapy (PDT) for colorectal cancer (CRC) and explores potential future directions in this field. PDT has emerged as a promising minimally invasive treatment modality that utilizes photosensitizers and specific light wavelengths to...

Descripción completa

Detalles Bibliográficos
Autores principales: Rodrigues, José A., Correia, José H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10418644/
https://www.ncbi.nlm.nih.gov/pubmed/37569580
http://dx.doi.org/10.3390/ijms241512204
_version_ 1785088314185875456
author Rodrigues, José A.
Correia, José H.
author_facet Rodrigues, José A.
Correia, José H.
author_sort Rodrigues, José A.
collection PubMed
description This review provides an update on the current state of photodynamic therapy (PDT) for colorectal cancer (CRC) and explores potential future directions in this field. PDT has emerged as a promising minimally invasive treatment modality that utilizes photosensitizers and specific light wavelengths to induce cell death in targeted tumor tissues. In recent years, significant progress has been made in understanding the underlying mechanisms, optimizing treatment protocols, and improving the efficacy of PDT for CRC. This article highlights key advancements in PDT techniques, including novel photosensitizers, light sources, and delivery methods. Furthermore, it discusses ongoing research efforts and potential future directions, such as combination therapies and nanotechnology-based approaches. By elucidating the current landscape and providing insights into future directions, this review aims to guide researchers and clinicians in harnessing the full potential of PDT for the effective management of CRC.
format Online
Article
Text
id pubmed-10418644
institution National Center for Biotechnology Information
language English
publishDate 2023
publisher MDPI
record_format MEDLINE/PubMed
spelling pubmed-104186442023-08-12 Photodynamic Therapy for Colorectal Cancer: An Update and a Look to the Future Rodrigues, José A. Correia, José H. Int J Mol Sci Review This review provides an update on the current state of photodynamic therapy (PDT) for colorectal cancer (CRC) and explores potential future directions in this field. PDT has emerged as a promising minimally invasive treatment modality that utilizes photosensitizers and specific light wavelengths to induce cell death in targeted tumor tissues. In recent years, significant progress has been made in understanding the underlying mechanisms, optimizing treatment protocols, and improving the efficacy of PDT for CRC. This article highlights key advancements in PDT techniques, including novel photosensitizers, light sources, and delivery methods. Furthermore, it discusses ongoing research efforts and potential future directions, such as combination therapies and nanotechnology-based approaches. By elucidating the current landscape and providing insights into future directions, this review aims to guide researchers and clinicians in harnessing the full potential of PDT for the effective management of CRC. MDPI 2023-07-30 /pmc/articles/PMC10418644/ /pubmed/37569580 http://dx.doi.org/10.3390/ijms241512204 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Rodrigues, José A.
Correia, José H.
Photodynamic Therapy for Colorectal Cancer: An Update and a Look to the Future
title Photodynamic Therapy for Colorectal Cancer: An Update and a Look to the Future
title_full Photodynamic Therapy for Colorectal Cancer: An Update and a Look to the Future
title_fullStr Photodynamic Therapy for Colorectal Cancer: An Update and a Look to the Future
title_full_unstemmed Photodynamic Therapy for Colorectal Cancer: An Update and a Look to the Future
title_short Photodynamic Therapy for Colorectal Cancer: An Update and a Look to the Future
title_sort photodynamic therapy for colorectal cancer: an update and a look to the future
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10418644/
https://www.ncbi.nlm.nih.gov/pubmed/37569580
http://dx.doi.org/10.3390/ijms241512204
work_keys_str_mv AT rodriguesjosea photodynamictherapyforcolorectalcanceranupdateandalooktothefuture
AT correiajoseh photodynamictherapyforcolorectalcanceranupdateandalooktothefuture