Ligand-Dependent Intramolecular Motion of Native Nicotinic Acetylcholine Receptors Determined in Living Myotube Cells via Diffracted X-ray Tracking

Nicotinic acetylcholine receptors (nAChRs) are ligand-gated ion channels that play an important role in signal transduction at the neuromuscular junction (NMJ). Movement of the nAChR extracellular domain following agonist binding induces conformational changes in the extracellular domain, which in t...

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Detalles Bibliográficos
Autores principales: Oishi, Koichiro, Nagamori, Mayu, Kashino, Yasuhiro, Sekiguchi, Hiroshi, Sasaki, Yuji C., Miyazawa, Atsuo, Nishino, Yuri
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10418694/
https://www.ncbi.nlm.nih.gov/pubmed/37569445
http://dx.doi.org/10.3390/ijms241512069

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