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Pharmacological Screening of Kv7.1 and Kv7.1/KCNE1 Activators as Potential Antiarrhythmic Drugs in the Zebrafish Heart
Long QT syndrome (LQTS) can lead to ventricular arrhythmia and sudden cardiac death. The most common congenital cause of LQTS is mutations in the channel subunits generating the cardiac potassium current I(Ks). Zebrafish (Danio rerio) have been proposed as a powerful system to model human cardiac di...
Autores principales: | De la Cruz, Alicia, Wu, Xiaoan, Rainer, Quinn C., Hiniesto-Iñigo, Irene, Perez, Marta E., Edler, Isak, Liin, Sara I., Larsson, H. Peter |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10418701/ https://www.ncbi.nlm.nih.gov/pubmed/37569465 http://dx.doi.org/10.3390/ijms241512092 |
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