CRISPR/Cas9: A Powerful Strategy to Improve CAR-T Cell Persistence

As an emerging treatment strategy for malignant tumors, chimeric antigen receptor T (CAR-T) cell therapy has been widely used in clinical practice, and its efficacy has been markedly improved in the past decade. However, the clinical effect of CAR-T therapy is not so satisfying, especially in solid...

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Detalles Bibliográficos
Autores principales: Wei, Wei, Chen, Zhi-Nan, Wang, Ke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10418799/
https://www.ncbi.nlm.nih.gov/pubmed/37569693
http://dx.doi.org/10.3390/ijms241512317

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