CSB Regulates Pathway Choice in Response to DNA Replication Stress Induced by Camptothecin

Topoisomerase inhibitor camptothecin (CPT) induces fork stalling and is highly toxic to proliferating cells. However, how cells respond to CPT-induced fork stalling has not been fully characterized. Here, we report that Cockayne syndrome group B (CSB) protein inhibits PRIMPOL-dependent fork reprimin...

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Detalles Bibliográficos
Autores principales: Batenburg, Nicole L., Walker, John R., Zhu, Xu-Dong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10418903/
https://www.ncbi.nlm.nih.gov/pubmed/37569794
http://dx.doi.org/10.3390/ijms241512419

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10418903/
https://www.ncbi.nlm.nih.gov/pubmed/37569794
http://dx.doi.org/10.3390/ijms241512419

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