Inhibition of CDK1 by RO-3306 Exhibits Anti-Tumorigenic Effects in Ovarian Cancer Cells and a Transgenic Mouse Model of Ovarian Cancer

Ovarian cancer is the deadliest gynecological malignancy of the reproductive organs in the United States. Cyclin-dependent kinase 1 (CDK1) is an important cell cycle regulatory protein that specifically controls the G2/M phase transition of the cell cycle. RO-3306 is a selective, ATP-competitive, an...

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Detalles Bibliográficos
Autores principales: Huang, Yu, Fan, Yali, Zhao, Ziyi, Zhang, Xin, Tucker, Katherine, Staley, Allison, Suo, Hongyan, Sun, Wenchuan, Shen, Xiaochang, Deng, Boer, Pierce, Stuart R., West, Lindsay, Yin, Yajie, Emanuele, Michael J., Zhou, Chunxiao, Bae-Jump, Victoria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10418904/
https://www.ncbi.nlm.nih.gov/pubmed/37569750
http://dx.doi.org/10.3390/ijms241512375

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10418904/
https://www.ncbi.nlm.nih.gov/pubmed/37569750
http://dx.doi.org/10.3390/ijms241512375

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