Cargando…
α-Synuclein Strains and Their Relevance to Parkinson’s Disease, Multiple System Atrophy, and Dementia with Lewy Bodies
Like many neurodegenerative diseases, Parkinson’s disease (PD) is characterized by the formation of proteinaceous aggregates in brain cells. In PD, those proteinaceous aggregates are formed by the α-synuclein (αSyn) and are considered the trademark of this neurodegenerative disease. In addition to P...
Autores principales: | Graves, Noah J., Gambin, Yann, Sierecki, Emma |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10418915/ https://www.ncbi.nlm.nih.gov/pubmed/37569510 http://dx.doi.org/10.3390/ijms241512134 |
Ejemplares similares
-
Selectivity of Lewy body protein interactions along the aggregation pathway of α-synuclein
por: Leitão, André D. G., et al.
Publicado: (2021) -
Different α-synuclein prion strains cause dementia with Lewy bodies and multiple system atrophy
por: Ayers, Jacob I., et al.
Publicado: (2022) -
The structural differences between patient-derived α-synuclein strains dictate characteristics of Parkinson’s disease, multiple system atrophy and dementia with Lewy bodies
por: Van der Perren, Anke, et al.
Publicado: (2020) -
Unveiling a Selective Mechanism for the Inhibition of α-Synuclein Aggregation by β-Synuclein
por: Leitao, Andre, et al.
Publicado: (2018) -
The synaptic pathology of α-synuclein aggregation in dementia with Lewy bodies, Parkinson’s disease and Parkinson’s disease dementia
por: Schulz-Schaeffer, Walter J.
Publicado: (2010)