Cargando…

Hmgb1 Silencing in the Amygdala Inhibits Pain-Related Behaviors in a Rat Model of Neuropathic Pain

Chronic pain presents a therapeutic challenge due to the highly complex interplay of sensory, emotional-affective and cognitive factors. The mechanisms of the transition from acute to chronic pain are not well understood. We hypothesized that neuroimmune mechanisms in the amygdala, a brain region in...

Descripción completa

Detalles Bibliográficos
Autores principales:	Presto, Peyton, Ji, Guangchen, Ponomareva, Olga, Ponomarev, Igor, Neugebauer, Volker
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10418916/ https://www.ncbi.nlm.nih.gov/pubmed/37569320 http://dx.doi.org/10.3390/ijms241511944

Ejemplares similares

Fear extinction learning ability predicts neuropathic pain behaviors and amygdala activity in male rats
por: Ji, Guangchen, et al.
Publicado: (2018)

Kappa Opioid Receptor Blockade in the Amygdala Mitigates Pain Like-Behaviors by Inhibiting Corticotropin Releasing Factor Neurons in a Rat Model of Functional Pain
por: Yakhnitsa, Vadim, et al.
Publicado: (2022)

Sex Differences in CGRP Regulation and Function in the Amygdala in a Rat Model of Neuropathic Pain
por: Presto, Peyton, et al.
Publicado: (2022)

Fear Extinction-Based Inter-Individual and Sex Differences in Pain-Related Vocalizations and Anxiety-like Behaviors but Not Nocifensive Reflexes
por: Presto, Peyton, et al.
Publicado: (2021)

Differential contributions of vasopressin V1A and oxytocin receptors in the amygdala to pain-related behaviors in rats
por: Cragg, Bryce, et al.
Publicado: (2016)

Nasal application of neuropeptide S inhibits arthritis pain-related behaviors through an action in the amygdala
por: Medina, Georgina, et al.
Publicado: (2014)

Contribution of Corticotropin-Releasing Factor Receptor 1 (CRF1) to Serotonin Receptor 5-HT(2C)R Function in Amygdala Neurons in a Neuropathic Pain Model
por: Ji, Guangchen, et al.
Publicado: (2019)

Facilitation of synaptic transmission and pain responses by CGRP in the amygdala of normal rats
por: Han, Jeong S, et al.
Publicado: (2010)

Pain-related anxiety-like behavior requires CRF1 receptors in the amygdala
por: Ji, Guangchen, et al.
Publicado: (2007)

Small-conductance calcium-activated potassium (SK) channels in the amygdala mediate pain-inhibiting effects of clinically available riluzole in a rat model of arthritis pain
por: Thompson, Jeremy M., et al.
Publicado: (2015)

NR2B receptor blockade inhibits pain-related sensitization of amygdala neurons
por: Ji, Guangchen, et al.
Publicado: (2009)

Non-pain-related CRF1 activation in the amygdala facilitates synaptic transmission and pain responses
por: Ji, Guangchen, et al.
Publicado: (2013)

Optogenetic Manipulations of Amygdala Neurons Modulate Spinal Nociceptive Processing and Behavior Under Normal Conditions and in an Arthritis Pain Model
por: Mazzitelli, Mariacristina, et al.
Publicado: (2021)

Kappa opioid receptors in the central amygdala modulate spinal nociceptive processing through an action on amygdala CRF neurons
por: Ji, Guangchen, et al.
Publicado: (2020)

Turmeric Bioactive Compounds Alleviate Spinal Nerve Ligation-Induced Neuropathic Pain by Suppressing Glial Activation and Improving Mitochondrial Function in Spinal Cord and Amygdala
por: Santos, Julianna M., et al.
Publicado: (2023)

Amygdala Plasticity and Pain
por: Thompson, Jeremy M., et al.
Publicado: (2017)

Basolateral Amygdala Lesion Inhibits the Development of Pain Chronicity in Neuropathic Pain Rats
por: Li, Zheng, et al.
Publicado: (2013)

Recent Advances in the Modulation of Pain by the Metabotropic Glutamate Receptors
por: Mazzitelli, Mariacristina, et al.
Publicado: (2022)

Two Curcumin Extracts Modify Composition of Gut Microbiota, Tight Junction Protein, and Neuroinflammation in Rats With Neuropathic Pain: Microbiota-Gut-Brain Axis
por: Shen, Chwan-Li, et al.
Publicado: (2022)

Ginger Root Extract Mitigates Neuropathic Pain via Suppressing Neuroinflammation: Gut-Brain Connection
por: Shen, Chwan-Li, et al.
Publicado: (2022)

PKA and ERK, but not PKC, in the amygdala contribute to pain-related synaptic plasticity and behavior
por: Fu, Yu, et al.
Publicado: (2008)

Techniques for assessing knee joint pain in arthritis
por: Neugebauer, Volker, et al.
Publicado: (2007)

Gingerol-Enriched Ginger Supplementation Mitigates Neuropathic Pain via Mitigating Intestinal Permeability and Neuroinflammation: Gut-Brain Connection
por: Shen, Chwan-Li, et al.
Publicado: (2022)

Electroacupuncture Attenuates Neuropathic Pain and Comorbid Negative Behavior: The Involvement of the Dopamine System in the Amygdala
por: Zhang, Xue-Hui, et al.
Publicado: (2021)

Homer1a signaling in the amygdala counteracts pain-related synaptic plasticity, mGluR1 function and pain behaviors
por: Tappe-Theodor, Anke, et al.
Publicado: (2011)

Dysfunction of Glutamate Delta-1 Receptor-Cerebellin 1 Trans-Synaptic Signaling in the Central Amygdala in Chronic Pain
por: Gandhi, Pauravi J., et al.
Publicado: (2021)

HMGB1 in the mPFC governs comorbid anxiety in neuropathic pain
por: Du, Yu, et al.
Publicado: (2022)

5-HT(2C)R blockade in the amygdala conveys analgesic efficacy to SSRIs in a rat model of arthritis pain
por: Grégoire, Stéphanie, et al.
Publicado: (2013)

Sensitization of neurons in the central nucleus of the amygdala via the decreased GABAergic inhibition contributes to the development of neuropathic pain-related anxiety-like behaviors in rats
por: Jiang, Hong, et al.
Publicado: (2014)

Enhanced group II mGluR-mediated inhibition of pain-related synaptic plasticity in the amygdala
por: Han, Jeong S, et al.
Publicado: (2006)

The Emerging Role of HMGB1 in Neuropathic Pain: A Potential Therapeutic Target for Neuroinflammation
por: Wan, Wenbin, et al.
Publicado: (2016)

Modulation of Hippocampal Astroglial Activity by Synaptamide in Rats with Neuropathic Pain
por: Manzhulo, Igor, et al.
Publicado: (2021)

Inhibition of CaMKIV relieves streptozotocin-induced diabetic neuropathic pain through regulation of HMGB1
por: Zhao, Xin, et al.
Publicado: (2016)

Mechanisms of Neuropathic Pain and Pain-Relieving Effects of Exercise Therapy in a Rat Neuropathic Pain Model
por: Sumizono, Megumi, et al.
Publicado: (2022)

The persistent release of HMGB1 contributes to tactile hyperalgesia in a rodent model of neuropathic pain
por: Feldman, Polina, et al.
Publicado: (2012)

Silencing of spinal Trpv1 attenuates neuropathic pain in rats by inhibiting CAMKII expression and ERK2 phosphorylation
por: Guo, Shao-Hui, et al.
Publicado: (2019)

Pain-related increase of excitatory transmission and decrease of inhibitory transmission in the central nucleus of the amygdala are mediated by mGluR1
por: Ren, Wenjie, et al.
Publicado: (2010)

Effect of Sildenafil on Neuropathic Pain and Hemodynamics in Rats
por: Huang, Lan Ji, et al.
Publicado: (2010)

Neuropathic Pain Induces Interleukin-1β Sensitive Bimodal Glycinergic Activity in the Central Amygdala
por: Oliva, Carolina A., et al.
Publicado: (2022)

Comparison of Burrowing and Stimuli-Evoked Pain Behaviors as End-Points in Rat Models of Inflammatory Pain and Peripheral Neuropathic Pain
por: Muralidharan, Arjun, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_1knou74v5v4ifhnts62276vga2