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Use of the Pessary in the Prevention of Preterm Delivery

Objective The gestational complication most associated with perinatal mortality and morbidity is spontaneous preterm birth with gestational age < 37 weeks. Therefore, it is necessary to identify its risk factors and attempt its prevention. The benefits of the pessary in prematurity are under inve...

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Autores principales: Corrêa, Thayane Delazari, Amorim, Ester Gomes, Tomazelli, Jade Aimée Guimarães, Corrêa, Mário Dias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Thieme Revinter Publicações Ltda 2019
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10418961/
https://www.ncbi.nlm.nih.gov/pubmed/30716786
http://dx.doi.org/10.1055/s-0038-1676511
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author Corrêa, Thayane Delazari
Amorim, Ester Gomes
Tomazelli, Jade Aimée Guimarães
Corrêa, Mário Dias
author_facet Corrêa, Thayane Delazari
Amorim, Ester Gomes
Tomazelli, Jade Aimée Guimarães
Corrêa, Mário Dias
author_sort Corrêa, Thayane Delazari
collection PubMed
description Objective The gestational complication most associated with perinatal mortality and morbidity is spontaneous preterm birth with gestational age < 37 weeks. Therefore, it is necessary to identify its risk factors and attempt its prevention. The benefits of the pessary in prematurity are under investigation. Our objective was to analyze the use of the pessary in the prevention of preterm births in published studies, and to compare its efficacy with other methods. Methods Randomized clinical trials published between 2010 and 2018 were selected from electronic databases. Studies on multiple gestations were excluded. Results Two studies were in favor of the pessary as a preventive method, one study was contrary to the method and another two showed no statistically significant difference. The meta-analysis showed no statistical difference with the use of a cervical pessary in the reduction of births < 37 (odds ratio [OR]: 0.63; confidence interval [95% CI]: 0.38–1.06) and < 34 weeks (OR: 0.74; 95% CI: 0.35–1.57) Conclusion The pooled data available to date seems to show a lack of efficacy of the cervical pessary in the prevention of preterm birth, although the heterogeneity of the studies made comparisons more difficult.
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spelling pubmed-104189612023-08-12 Use of the Pessary in the Prevention of Preterm Delivery Corrêa, Thayane Delazari Amorim, Ester Gomes Tomazelli, Jade Aimée Guimarães Corrêa, Mário Dias Rev Bras Ginecol Obstet Objective The gestational complication most associated with perinatal mortality and morbidity is spontaneous preterm birth with gestational age < 37 weeks. Therefore, it is necessary to identify its risk factors and attempt its prevention. The benefits of the pessary in prematurity are under investigation. Our objective was to analyze the use of the pessary in the prevention of preterm births in published studies, and to compare its efficacy with other methods. Methods Randomized clinical trials published between 2010 and 2018 were selected from electronic databases. Studies on multiple gestations were excluded. Results Two studies were in favor of the pessary as a preventive method, one study was contrary to the method and another two showed no statistically significant difference. The meta-analysis showed no statistical difference with the use of a cervical pessary in the reduction of births < 37 (odds ratio [OR]: 0.63; confidence interval [95% CI]: 0.38–1.06) and < 34 weeks (OR: 0.74; 95% CI: 0.35–1.57) Conclusion The pooled data available to date seems to show a lack of efficacy of the cervical pessary in the prevention of preterm birth, although the heterogeneity of the studies made comparisons more difficult. Thieme Revinter Publicações Ltda 2019-01 /pmc/articles/PMC10418961/ /pubmed/30716786 http://dx.doi.org/10.1055/s-0038-1676511 Text en https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Corrêa, Thayane Delazari
Amorim, Ester Gomes
Tomazelli, Jade Aimée Guimarães
Corrêa, Mário Dias
Use of the Pessary in the Prevention of Preterm Delivery
title Use of the Pessary in the Prevention of Preterm Delivery
title_full Use of the Pessary in the Prevention of Preterm Delivery
title_fullStr Use of the Pessary in the Prevention of Preterm Delivery
title_full_unstemmed Use of the Pessary in the Prevention of Preterm Delivery
title_short Use of the Pessary in the Prevention of Preterm Delivery
title_sort use of the pessary in the prevention of preterm delivery
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10418961/
https://www.ncbi.nlm.nih.gov/pubmed/30716786
http://dx.doi.org/10.1055/s-0038-1676511
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