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SPARC Is Highly Expressed in Young Skin and Promotes Extracellular Matrix Integrity in Fibroblasts via the TGF-β Signaling Pathway

The matricellular secreted protein acidic and rich in cysteine (SPARC; also known as osteonectin), is involved in the regulation of extracellular matrix (ECM) synthesis, cell-ECM interactions, and bone mineralization. We found decreased SPARC expression in aged skin. Incubating foreskin fibroblasts...

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Detalles Bibliográficos
Autores principales:	Ham, Seung Min, Song, Min Ji, Yoon, Hyun-Sun, Lee, Dong Hun, Chung, Jin Ho, Lee, Seung-Taek
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10419001/ https://www.ncbi.nlm.nih.gov/pubmed/37569556 http://dx.doi.org/10.3390/ijms241512179

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