Contemporary Antiretroviral Therapy Dysregulates Iron Transport and Augments Mitochondrial Dysfunction in HIV-Infected Human Microglia and Neural-Lineage Cells

HIV-associated cognitive dysfunction during combination antiretroviral therapy (cART) involves mitochondrial dysfunction, but the impact of contemporary cART on chronic metabolic changes in the brain and in latent HIV infection is unclear. We interrogated mitochondrial function in a human microglia...

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Detalles Bibliográficos
Autores principales: Kaur, Harpreet, Minchella, Paige, Alvarez-Carbonell, David, Purandare, Neeraja, Nagampalli, Vijay K., Blankenberg, Daniel, Hulgan, Todd, Gerschenson, Mariana, Karn, Jonathan, Aras, Siddhesh, Kallianpur, Asha R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10419149/
https://www.ncbi.nlm.nih.gov/pubmed/37569616
http://dx.doi.org/10.3390/ijms241512242

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10419149/
https://www.ncbi.nlm.nih.gov/pubmed/37569616
http://dx.doi.org/10.3390/ijms241512242

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