Cargando…

SPARC: a potential target for functional nanomaterials and drugs

Secreted protein acidic and rich in cysteine (SPARC), also termed osteonectin or BM-40, is a matricellular protein which regulates cell adhesion, extracellular matrix production, growth factor activity, and cell cycle. Although SPARC does not perform a structural function, it, however, modulates int...

Descripción completa

Detalles Bibliográficos
Autores principales:	Jiang, Shan, Sun, Hui-Feng, Li, Shuang, Zhang, Ning, Chen, Ji-Song, Liu, Jian-Xin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2023
Materias:	Molecular Biosciences
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10419254/ https://www.ncbi.nlm.nih.gov/pubmed/37577749 http://dx.doi.org/10.3389/fmolb.2023.1235428

Ejemplares similares

SPARC Overexpression Promotes Liver Cancer Cell Proliferation and Tumor Growth
por: Gao, Zhao-wei, et al.
Publicado: (2021)

Development of Nanomaterials to Target Articular Cartilage for Osteoarthritis Therapy
por: Rao, Chenyu, et al.
Publicado: (2022)

Advanced bioactive nanomaterials for diagnosis and treatment of major chronic diseases
por: Liu, Yongfei, et al.
Publicado: (2023)

ADAMTS5 in Osteoarthritis: Biological Functions, Regulatory Network, and Potential Targeting Therapies
por: Jiang, Lejian, et al.
Publicado: (2021)

Applications of Alginate-Based Nanomaterials in Enhancing the Therapeutic Effects of Bee Products
por: Al-Hatamleh, Mohammad A. I., et al.
Publicado: (2022)

Hybrid neural network approaches to predict drug–target binding affinity for drug repurposing: screening for potential leads for Alzheimer’s disease
por: Wu, Xialin, et al.
Publicado: (2023)

Identification of Alternative Allosteric Sites in Glycolytic Enzymes for Potential Use as Species-Specific Drug Targets
por: Ayyildiz, Merve, et al.
Publicado: (2020)

HSP70 and their co-chaperones in the human malaria parasite P. falciparum and their potential as drug targets
por: Barth, Julian, et al.
Publicado: (2022)

Role of Transient Receptor Potential Vanilloid 4 in Vascular Function
por: Liu, Liangliang, et al.
Publicado: (2021)

AMPK as a Potential Therapeutic Target for Intervertebral Disc Degeneration
por: Wang, Zhen, et al.
Publicado: (2021)

Identification of a 3-Gene Prognostic Index for Papillary Thyroid Carcinoma
por: Zhong, Lin-Kun, et al.
Publicado: (2022)

Inteins as Drug Targets and Therapeutic Tools
por: Tharappel, Anil Mathew, et al.
Publicado: (2022)

Natural antisense transcripts as drug targets
por: Khorkova, Olga, et al.
Publicado: (2022)

Identification of Potential Genomic Alterations and the circRNA-miRNA-mRNA Regulatory Network in Primary and Recurrent Synovial Sarcomas
por: Yao, Qing, et al.
Publicado: (2021)

CLEC3B as a Potential Prognostic Biomarker in Hepatocellular Carcinoma
por: Xie, Xing-Wei, et al.
Publicado: (2021)

Integrative Analysis of MALT1 as a Potential Therapeutic Target for Prostate Cancer and its Immunological Role in Pan-Cancer
por: Tan, Haotian, et al.
Publicado: (2021)

Exosomes: Potential Biomarkers and Functions in Head and Neck Squamous Cell Carcinoma
por: Li, Ting, et al.
Publicado: (2022)

Hsp70 Is a Potential Therapeutic Target for Echovirus 9 Infection
por: Wang, Yang, et al.
Publicado: (2020)

Identification of potential target genes of breast cancer in response to Chidamide treatment
por: Han, Han, et al.
Publicado: (2022)

Corrigendum: Exosomes: Potential biomarkers and functions in head and neck squamous cell carcinoma
por: Li, Ting, et al.
Publicado: (2022)

A Systematic Pan-Cancer Analysis of CASP3 as a Potential Target for Immunotherapy
por: Zhou, Zheng, et al.
Publicado: (2022)

Application of Fragment-Based Drug Discovery to Versatile Targets
por: Li, Qingxin
Publicado: (2020)

Targeting the ubiquitin system by fragment-based drug discovery
por: Kennedy, Cassandra, et al.
Publicado: (2022)

Targeting hedgehog-driven mechanisms of drug-resistant cancers
por: Miller, Jade S., et al.
Publicado: (2023)

Gene expression, molecular docking, and molecular dynamics studies to identify potential antifungal compounds targeting virulence proteins/genes VelB and THR as possible drug targets against Curvularia lunata
por: Kamboj, Himanshu, et al.
Publicado: (2022)

Principles and functions of condensate modifying drugs
por: Patel, Avinash, et al.
Publicado: (2022)

Screening for Potential Therapeutic Agents for Non-Small Cell Lung Cancer by Targeting Ferroptosis
por: Zhao, Xin, et al.
Publicado: (2022)

SLC7A11, a Potential Therapeutic Target Through Induced Ferroptosis in Colon Adenocarcinoma
por: Cheng, Xin, et al.
Publicado: (2022)

Functional Expression of the Human Glucose Transporters GLUT2 and GLUT3 in Yeast Offers Novel Screening Systems for GLUT-Targeting Drugs
por: Schmidl, Sina, et al.
Publicado: (2021)

Inhibitors of riboflavin biosynthetic pathway enzymes as potential antibacterial drugs
por: Islam, Zeyaul, et al.
Publicado: (2023)

Drug affinity-responsive target stability unveils filamins as biological targets for artemetin, an anti-cancer flavonoid
por: Ferraro, Giusy, et al.
Publicado: (2022)

The potential of PARP inhibitors in targeted cancer therapy and immunotherapy
por: Hunia, Jaromir, et al.
Publicado: (2022)

Identification of NUDT5 Inhibitors From Approved Drugs
por: Tong, Xin-Yu, et al.
Publicado: (2020)

MiR-92a Family: A Novel Diagnostic Biomarker and Potential Therapeutic Target in Human Cancers
por: Jiang, Min, et al.
Publicado: (2019)

Off-Target Effects of Drugs that Disrupt Human Mitochondrial DNA Maintenance
por: Young, Matthew J.
Publicado: (2017)

Evaluation of Clove Phytochemicals as Potential Antiviral Drug Candidates Targeting SARS-CoV-2 Main Protease: Computational Docking, Molecular Dynamics Simulation, and Pharmacokinetic Profiling
por: Chandra Manivannan, Arun, et al.
Publicado: (2022)

Editorial: Antiviral drug discovery against pathogens of pandemic concern: Advancements in target site identification and structure-based drug development
por: Padmanabha Das, Krishna M.
Publicado: (2023)

Systematic Identification of Anti-Fungal Drug Targets by a Metabolic Network Approach
por: Kaltdorf, Martin, et al.
Publicado: (2016)

Comparing the Nucleocapsid Proteins of Human Coronaviruses: Structure, Immunoregulation, Vaccine, and Targeted Drug
por: Zhang, Bo, et al.
Publicado: (2022)

Editorial: “Small molecules targeting transmembrane receptors and ion channels in drug discovery”
por: Vitale, Rosa Maria, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_5kbr9afla3giu28fklppocit16