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Virtual Reality Technology to Enhance Conventional Rehabilitation Program: Results of a Single-Blind, Randomized, Controlled Pilot Study in Patients with Global Developmental Delay

Global developmental delay (GDD) is a complex disorder that requires multimodal treatment involving different developmental skills. The objective of this single-blind, randomized, controlled pilot study is to evaluate the feasibility and effectiveness of conventional rehabilitation programs integrat...

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Autores principales: Settimo, Carmela, De Cola, Maria Cristina, Pironti, Erica, Muratore, Rosalia, Giambò, Fabio Mauro, Alito, Angelo, Tresoldi, Maria, La Fauci, Margherita, De Domenico, Carmela, Tripodi, Emanuela, Impallomeni, Caterina, Quartarone, Angelo, Cucinotta, Francesca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10419390/
https://www.ncbi.nlm.nih.gov/pubmed/37568364
http://dx.doi.org/10.3390/jcm12154962
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author Settimo, Carmela
De Cola, Maria Cristina
Pironti, Erica
Muratore, Rosalia
Giambò, Fabio Mauro
Alito, Angelo
Tresoldi, Maria
La Fauci, Margherita
De Domenico, Carmela
Tripodi, Emanuela
Impallomeni, Caterina
Quartarone, Angelo
Cucinotta, Francesca
author_facet Settimo, Carmela
De Cola, Maria Cristina
Pironti, Erica
Muratore, Rosalia
Giambò, Fabio Mauro
Alito, Angelo
Tresoldi, Maria
La Fauci, Margherita
De Domenico, Carmela
Tripodi, Emanuela
Impallomeni, Caterina
Quartarone, Angelo
Cucinotta, Francesca
author_sort Settimo, Carmela
collection PubMed
description Global developmental delay (GDD) is a complex disorder that requires multimodal treatment involving different developmental skills. The objective of this single-blind, randomized, controlled pilot study is to evaluate the feasibility and effectiveness of conventional rehabilitation programs integrated with the BTs-Nirvana virtual reality system. Patients with GDD aged 12 to 66 months were enrolled and treated for a 48-session cycle. Patients were randomized into two groups, (1) conventional treatment and (2) conventional treatment supplemented with the use of BTs-Nirvana, in a 1:1 ratio. Before and after treatments, areas of global development were tested with the Griffiths-III Mental Developmental Scale and the clinical indicator of global improvement were measured with the Clinical Global Impressions-Improvement (CGI-I). Feasibility was confirmed by the high retention rate. The experimental group presented a significantly improvement in General Quotient (GQ) after treatment (GQ, p = 0.02), and the effect of the two treatments was significantly different in both the GQ (t =2.44; p = 0.02) and the Foundations of Learning subscale (t =3.66; p < 0.01). The overall improvement was also confirmed by the CGI-I (p = 0.03). According to these preliminary data, virtual reality can be considered a useful complementary tool to boost the effectiveness of conventional therapy in children with GDD.
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spelling pubmed-104193902023-08-12 Virtual Reality Technology to Enhance Conventional Rehabilitation Program: Results of a Single-Blind, Randomized, Controlled Pilot Study in Patients with Global Developmental Delay Settimo, Carmela De Cola, Maria Cristina Pironti, Erica Muratore, Rosalia Giambò, Fabio Mauro Alito, Angelo Tresoldi, Maria La Fauci, Margherita De Domenico, Carmela Tripodi, Emanuela Impallomeni, Caterina Quartarone, Angelo Cucinotta, Francesca J Clin Med Article Global developmental delay (GDD) is a complex disorder that requires multimodal treatment involving different developmental skills. The objective of this single-blind, randomized, controlled pilot study is to evaluate the feasibility and effectiveness of conventional rehabilitation programs integrated with the BTs-Nirvana virtual reality system. Patients with GDD aged 12 to 66 months were enrolled and treated for a 48-session cycle. Patients were randomized into two groups, (1) conventional treatment and (2) conventional treatment supplemented with the use of BTs-Nirvana, in a 1:1 ratio. Before and after treatments, areas of global development were tested with the Griffiths-III Mental Developmental Scale and the clinical indicator of global improvement were measured with the Clinical Global Impressions-Improvement (CGI-I). Feasibility was confirmed by the high retention rate. The experimental group presented a significantly improvement in General Quotient (GQ) after treatment (GQ, p = 0.02), and the effect of the two treatments was significantly different in both the GQ (t =2.44; p = 0.02) and the Foundations of Learning subscale (t =3.66; p < 0.01). The overall improvement was also confirmed by the CGI-I (p = 0.03). According to these preliminary data, virtual reality can be considered a useful complementary tool to boost the effectiveness of conventional therapy in children with GDD. MDPI 2023-07-28 /pmc/articles/PMC10419390/ /pubmed/37568364 http://dx.doi.org/10.3390/jcm12154962 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Settimo, Carmela
De Cola, Maria Cristina
Pironti, Erica
Muratore, Rosalia
Giambò, Fabio Mauro
Alito, Angelo
Tresoldi, Maria
La Fauci, Margherita
De Domenico, Carmela
Tripodi, Emanuela
Impallomeni, Caterina
Quartarone, Angelo
Cucinotta, Francesca
Virtual Reality Technology to Enhance Conventional Rehabilitation Program: Results of a Single-Blind, Randomized, Controlled Pilot Study in Patients with Global Developmental Delay
title Virtual Reality Technology to Enhance Conventional Rehabilitation Program: Results of a Single-Blind, Randomized, Controlled Pilot Study in Patients with Global Developmental Delay
title_full Virtual Reality Technology to Enhance Conventional Rehabilitation Program: Results of a Single-Blind, Randomized, Controlled Pilot Study in Patients with Global Developmental Delay
title_fullStr Virtual Reality Technology to Enhance Conventional Rehabilitation Program: Results of a Single-Blind, Randomized, Controlled Pilot Study in Patients with Global Developmental Delay
title_full_unstemmed Virtual Reality Technology to Enhance Conventional Rehabilitation Program: Results of a Single-Blind, Randomized, Controlled Pilot Study in Patients with Global Developmental Delay
title_short Virtual Reality Technology to Enhance Conventional Rehabilitation Program: Results of a Single-Blind, Randomized, Controlled Pilot Study in Patients with Global Developmental Delay
title_sort virtual reality technology to enhance conventional rehabilitation program: results of a single-blind, randomized, controlled pilot study in patients with global developmental delay
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10419390/
https://www.ncbi.nlm.nih.gov/pubmed/37568364
http://dx.doi.org/10.3390/jcm12154962
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