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Recurrent squamous cell carcinoma arising in ovary mature cystic teratoma: A case report

Malignant transformation of mature cystic teratoma is very rare, of which squamous cell carcinoma (SCC) is the most common type. Prognosis of SCC arising in mature cystic teratoma of the ovary is very poor. Our experience may provide new ideas for the treatment of this disease. PATIENT CONCERNS: The...

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Autores principales: Ji, Xuechao, Zhai, Peiling, Yang, Hanchao, Wang, Hui, Wang, Xinbo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10419499/
https://www.ncbi.nlm.nih.gov/pubmed/37565860
http://dx.doi.org/10.1097/MD.0000000000034734
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author Ji, Xuechao
Zhai, Peiling
Yang, Hanchao
Wang, Hui
Wang, Xinbo
author_facet Ji, Xuechao
Zhai, Peiling
Yang, Hanchao
Wang, Hui
Wang, Xinbo
author_sort Ji, Xuechao
collection PubMed
description Malignant transformation of mature cystic teratoma is very rare, of which squamous cell carcinoma (SCC) is the most common type. Prognosis of SCC arising in mature cystic teratoma of the ovary is very poor. Our experience may provide new ideas for the treatment of this disease. PATIENT CONCERNS: The patient was a 56-year-old woman and was admitted for a lower abdominal pain. She underwent a laparoscopic surgery with 4 cycles of chemotherapy and had achieved a complete response; 10 months after the completion of initial treatment, her cancer relapsed. She underwent a cytoreductive surgery with concurrent chemoradiotherapy and has achieved a complete response again. DIAGNOSES: This patient was initially diagnosed with ovarian cancer (stage IIIB) arising from malignant transformation of mature teratoma; 10 months after the completion of initial treatment, she was diagnosed with recurrent ovarian cancer. INTERVENTIONS: This patient was initially treated with laparoscopic bilateral salpingo-oophorectomy. After histopathological confirmation that she had ovarian cancer, she underwent laparoscopic total hysterectomy and omentectomy with 4 cycles of chemotherapy. After her ovarian cancer recurred, she underwent open cytoreductive surgery and concurrent chemoradiotherapy. OUTCOMES: The patient achieved complete response after both initial and relapsed treatment. LESSONS: Optimal cytoreduction and concurrent chemoradiotherapy may be an option to improve the prognosis of patients with recurrent SCC arising in ovary mature cystic teratoma.
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spelling pubmed-104194992023-08-12 Recurrent squamous cell carcinoma arising in ovary mature cystic teratoma: A case report Ji, Xuechao Zhai, Peiling Yang, Hanchao Wang, Hui Wang, Xinbo Medicine (Baltimore) 5600 Malignant transformation of mature cystic teratoma is very rare, of which squamous cell carcinoma (SCC) is the most common type. Prognosis of SCC arising in mature cystic teratoma of the ovary is very poor. Our experience may provide new ideas for the treatment of this disease. PATIENT CONCERNS: The patient was a 56-year-old woman and was admitted for a lower abdominal pain. She underwent a laparoscopic surgery with 4 cycles of chemotherapy and had achieved a complete response; 10 months after the completion of initial treatment, her cancer relapsed. She underwent a cytoreductive surgery with concurrent chemoradiotherapy and has achieved a complete response again. DIAGNOSES: This patient was initially diagnosed with ovarian cancer (stage IIIB) arising from malignant transformation of mature teratoma; 10 months after the completion of initial treatment, she was diagnosed with recurrent ovarian cancer. INTERVENTIONS: This patient was initially treated with laparoscopic bilateral salpingo-oophorectomy. After histopathological confirmation that she had ovarian cancer, she underwent laparoscopic total hysterectomy and omentectomy with 4 cycles of chemotherapy. After her ovarian cancer recurred, she underwent open cytoreductive surgery and concurrent chemoradiotherapy. OUTCOMES: The patient achieved complete response after both initial and relapsed treatment. LESSONS: Optimal cytoreduction and concurrent chemoradiotherapy may be an option to improve the prognosis of patients with recurrent SCC arising in ovary mature cystic teratoma. Lippincott Williams & Wilkins 2023-08-11 /pmc/articles/PMC10419499/ /pubmed/37565860 http://dx.doi.org/10.1097/MD.0000000000034734 Text en Copyright © 2023 the Author(s). Published by Wolters Kluwer Health, Inc. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the Creative Commons Attribution License 4.0 (CCBY) (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle 5600
Ji, Xuechao
Zhai, Peiling
Yang, Hanchao
Wang, Hui
Wang, Xinbo
Recurrent squamous cell carcinoma arising in ovary mature cystic teratoma: A case report
title Recurrent squamous cell carcinoma arising in ovary mature cystic teratoma: A case report
title_full Recurrent squamous cell carcinoma arising in ovary mature cystic teratoma: A case report
title_fullStr Recurrent squamous cell carcinoma arising in ovary mature cystic teratoma: A case report
title_full_unstemmed Recurrent squamous cell carcinoma arising in ovary mature cystic teratoma: A case report
title_short Recurrent squamous cell carcinoma arising in ovary mature cystic teratoma: A case report
title_sort recurrent squamous cell carcinoma arising in ovary mature cystic teratoma: a case report
topic 5600
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10419499/
https://www.ncbi.nlm.nih.gov/pubmed/37565860
http://dx.doi.org/10.1097/MD.0000000000034734
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