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Significance of Five-Membered Heterocycles in Human Histone Deacetylase Inhibitors
Five-membered heteroaromatic rings, in particular, have gained prominence in medicinal chemistry as they offer enhanced metabolic stability, solubility and bioavailability, crucial factors in developing effective drugs. The unique physicochemical properties and biological effects of five-membered he...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10419652/ https://www.ncbi.nlm.nih.gov/pubmed/37570656 http://dx.doi.org/10.3390/molecules28155686 |