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Significance of Five-Membered Heterocycles in Human Histone Deacetylase Inhibitors

Five-membered heteroaromatic rings, in particular, have gained prominence in medicinal chemistry as they offer enhanced metabolic stability, solubility and bioavailability, crucial factors in developing effective drugs. The unique physicochemical properties and biological effects of five-membered he...

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Detalles Bibliográficos
Autores principales:	Frühauf, Anton, Behringer, Martin, Meyer-Almes, Franz-Josef
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10419652/ https://www.ncbi.nlm.nih.gov/pubmed/37570656 http://dx.doi.org/10.3390/molecules28155686

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