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Multivariate Analysis of Effective Dose and Size-Specific Dose Estimates for Thorax and Abdominal Computed Tomography

The study aimed to compute the effective dose (E) and size-specific dose estimate (SSDE) of routine adult patients undergoing thorax and abdominal computed tomography (CT) imaging and to present their multivariate analysis. All adult thorax and abdominal CT examinations conducted from March 2022 to...

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Autores principales: Shah, Mudasir Ashraf, Ahmad, Mehtab, Khalid, Saifullah, Qaseem, Syed M. Danish, Siddiqui, Shaista, Talib, Sayema, Rather, Sajad Ahmed, Firdous, Arfat
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10419744/
https://www.ncbi.nlm.nih.gov/pubmed/37576100
http://dx.doi.org/10.4103/jmp.jmp_102_22
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author Shah, Mudasir Ashraf
Ahmad, Mehtab
Khalid, Saifullah
Qaseem, Syed M. Danish
Siddiqui, Shaista
Talib, Sayema
Rather, Sajad Ahmed
Firdous, Arfat
author_facet Shah, Mudasir Ashraf
Ahmad, Mehtab
Khalid, Saifullah
Qaseem, Syed M. Danish
Siddiqui, Shaista
Talib, Sayema
Rather, Sajad Ahmed
Firdous, Arfat
author_sort Shah, Mudasir Ashraf
collection PubMed
description The study aimed to compute the effective dose (E) and size-specific dose estimate (SSDE) of routine adult patients undergoing thorax and abdominal computed tomography (CT) imaging and to present their multivariate analysis. All adult thorax and abdominal CT examinations conducted from March 2022 to June 2022 were prospectively included in this study. The Water Equivalent Diameter (D(w)) and SSDE of all the examinations were computed from CT dose index volume (CTDI(vol)) and Dose length product (DLP) displayed on the dose report in the CT console. The multivariate statistical analysis was performed to investigate the correlation of SSDE and E on CTDI(vol), D(w) area of the region of interest (ROI) (Area(ROI)), body mass index (BMI), conversion factor (f(size)) and hounsfield (HU(mean)) number in the ROI at 95% level of significance (P < 0.05). The linear regression analysis was performed to investigate the dependence of SSDE and E on other parameters for both abdominal and thorax patients. A total number of 135 (Abdomen = 61 and Thorax = 74) measurements were performed. The mean value of effective dose for abdomen and thorax patients was found to be 7.17 ± 3.94 and 4.89 ± 2.16 mSv, respectively. The SSDE was observed to be 13.24 ± 3.61 and 13.04 ± 3.61 mGy for thorax and abdomen respectively. The multivariate analysis suggests that SSDE for abdominal CT is found significantly dependent on CTDI(vol), D(w) and f(size) with P < 0.05 and E is found to be significantly dependent on DLP, Area(ROI), D(w) and f(size) at 95% level of confidence for abdominal CT imaging. SSDE for thorax CT was found significantly dependent on BMI, CTDI(vol), HU(mean), D(w) and f(size) at 95% level of confidence. Furthermore, E was observed dependent on DLP at P < 0.05. The linear regression analysis also shows that E is strongly correlated with DLP (r = 1.0) for both thorax and abdominal CT, further the SSDE was observed strongly correlated with CTDI(vol) with r = 0.79 and r = 0.86 for abdomen and thorax CT respectively. A strong correlation was observed between BMI and for D(w) abdominal CT imaging (r = 0.68). The mean value of SSDE for thorax is slightly greater than abdomen. The average value of effective dose for abdomen and thorax measurements was found to be 7.17 ± 3.94 and 4.89 ± 2.16 mSv and , correspondingly. SSDE for both abdomen and thorax CT is significantly dependent on CTDI(vol), D(w) and f(size) at 95% level of confidence. The strong correlation was also observed E on DLP and SSDE on CTDI(vol) for both Abdomen and Thorax CT. The strong dependence of D(w) on BMI (r = 0.68) is due to the excessive fat concentration around the stomach and abdomen.
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spelling pubmed-104197442023-08-12 Multivariate Analysis of Effective Dose and Size-Specific Dose Estimates for Thorax and Abdominal Computed Tomography Shah, Mudasir Ashraf Ahmad, Mehtab Khalid, Saifullah Qaseem, Syed M. Danish Siddiqui, Shaista Talib, Sayema Rather, Sajad Ahmed Firdous, Arfat J Med Phys Technical Note The study aimed to compute the effective dose (E) and size-specific dose estimate (SSDE) of routine adult patients undergoing thorax and abdominal computed tomography (CT) imaging and to present their multivariate analysis. All adult thorax and abdominal CT examinations conducted from March 2022 to June 2022 were prospectively included in this study. The Water Equivalent Diameter (D(w)) and SSDE of all the examinations were computed from CT dose index volume (CTDI(vol)) and Dose length product (DLP) displayed on the dose report in the CT console. The multivariate statistical analysis was performed to investigate the correlation of SSDE and E on CTDI(vol), D(w) area of the region of interest (ROI) (Area(ROI)), body mass index (BMI), conversion factor (f(size)) and hounsfield (HU(mean)) number in the ROI at 95% level of significance (P < 0.05). The linear regression analysis was performed to investigate the dependence of SSDE and E on other parameters for both abdominal and thorax patients. A total number of 135 (Abdomen = 61 and Thorax = 74) measurements were performed. The mean value of effective dose for abdomen and thorax patients was found to be 7.17 ± 3.94 and 4.89 ± 2.16 mSv, respectively. The SSDE was observed to be 13.24 ± 3.61 and 13.04 ± 3.61 mGy for thorax and abdomen respectively. The multivariate analysis suggests that SSDE for abdominal CT is found significantly dependent on CTDI(vol), D(w) and f(size) with P < 0.05 and E is found to be significantly dependent on DLP, Area(ROI), D(w) and f(size) at 95% level of confidence for abdominal CT imaging. SSDE for thorax CT was found significantly dependent on BMI, CTDI(vol), HU(mean), D(w) and f(size) at 95% level of confidence. Furthermore, E was observed dependent on DLP at P < 0.05. The linear regression analysis also shows that E is strongly correlated with DLP (r = 1.0) for both thorax and abdominal CT, further the SSDE was observed strongly correlated with CTDI(vol) with r = 0.79 and r = 0.86 for abdomen and thorax CT respectively. A strong correlation was observed between BMI and for D(w) abdominal CT imaging (r = 0.68). The mean value of SSDE for thorax is slightly greater than abdomen. The average value of effective dose for abdomen and thorax measurements was found to be 7.17 ± 3.94 and 4.89 ± 2.16 mSv and , correspondingly. SSDE for both abdomen and thorax CT is significantly dependent on CTDI(vol), D(w) and f(size) at 95% level of confidence. The strong correlation was also observed E on DLP and SSDE on CTDI(vol) for both Abdomen and Thorax CT. The strong dependence of D(w) on BMI (r = 0.68) is due to the excessive fat concentration around the stomach and abdomen. Wolters Kluwer - Medknow 2023 2023-06-29 /pmc/articles/PMC10419744/ /pubmed/37576100 http://dx.doi.org/10.4103/jmp.jmp_102_22 Text en Copyright: © 2023 Journal of Medical Physics https://creativecommons.org/licenses/by-nc-sa/4.0/This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
spellingShingle Technical Note
Shah, Mudasir Ashraf
Ahmad, Mehtab
Khalid, Saifullah
Qaseem, Syed M. Danish
Siddiqui, Shaista
Talib, Sayema
Rather, Sajad Ahmed
Firdous, Arfat
Multivariate Analysis of Effective Dose and Size-Specific Dose Estimates for Thorax and Abdominal Computed Tomography
title Multivariate Analysis of Effective Dose and Size-Specific Dose Estimates for Thorax and Abdominal Computed Tomography
title_full Multivariate Analysis of Effective Dose and Size-Specific Dose Estimates for Thorax and Abdominal Computed Tomography
title_fullStr Multivariate Analysis of Effective Dose and Size-Specific Dose Estimates for Thorax and Abdominal Computed Tomography
title_full_unstemmed Multivariate Analysis of Effective Dose and Size-Specific Dose Estimates for Thorax and Abdominal Computed Tomography
title_short Multivariate Analysis of Effective Dose and Size-Specific Dose Estimates for Thorax and Abdominal Computed Tomography
title_sort multivariate analysis of effective dose and size-specific dose estimates for thorax and abdominal computed tomography
topic Technical Note
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10419744/
https://www.ncbi.nlm.nih.gov/pubmed/37576100
http://dx.doi.org/10.4103/jmp.jmp_102_22
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