A multilocus genetic risk score for obesity: Association with BMI and metabolic alterations in a cohort with severe obesity

Genome wide association studies have identified numerous single nucleotide polymorphisms (SNPs) associated with obesity, yet effect sizes of individual SNPs are small. Therefore, the aim of our study was to investigate whether a genetic risk score (GRS) comprising risk alleles of SNPs identified in...

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Detalles Bibliográficos
Autores principales: Sag, Sabine Julia Maria, Mueller, Stephanie, Wallner, Stefan, Strack, Christina, Hubauer, Ute, Mohr, Margareta, Zeller, Judith, Loew, Thomas, Rehli, Michael, Wimmer, Julia, Zimmermann, Martina Erika, Maier, Lars Siegfried, Fischer, Marcus, Baessler, Andrea
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2023
Materias:
3500
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10419793/
https://www.ncbi.nlm.nih.gov/pubmed/37565910
http://dx.doi.org/10.1097/MD.0000000000034597

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