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Phytochemical Properties, Extraction, and Pharmacological Benefits of Naringin: A Review

This review describes the various innovative approaches implemented for naringin extraction as well as the recent developments in the field. Naringin was assessed in terms of its structure, chemical composition, and potential food sources. How naringin works pharmacologically was discussed, includin...

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Autores principales: Shilpa, VS, Shams, Rafeeya, Dash, Kshirod Kumar, Pandey, Vinay Kumar, Dar, Aamir Hussain, Ayaz Mukarram, Shaikh, Harsányi, Endre, Kovács, Béla
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10419872/
https://www.ncbi.nlm.nih.gov/pubmed/37570594
http://dx.doi.org/10.3390/molecules28155623
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author Shilpa, VS
Shams, Rafeeya
Dash, Kshirod Kumar
Pandey, Vinay Kumar
Dar, Aamir Hussain
Ayaz Mukarram, Shaikh
Harsányi, Endre
Kovács, Béla
author_facet Shilpa, VS
Shams, Rafeeya
Dash, Kshirod Kumar
Pandey, Vinay Kumar
Dar, Aamir Hussain
Ayaz Mukarram, Shaikh
Harsányi, Endre
Kovács, Béla
author_sort Shilpa, VS
collection PubMed
description This review describes the various innovative approaches implemented for naringin extraction as well as the recent developments in the field. Naringin was assessed in terms of its structure, chemical composition, and potential food sources. How naringin works pharmacologically was discussed, including its potential as an anti-diabetic, anti-inflammatory, and hepatoprotective substance. Citrus flavonoids are crucial herbal additives that have a huge spectrum of organic activities. Naringin is a nutritional flavanone glycoside that has been shown to be effective in the treatment of a few chronic disorders associated with ageing. Citrus fruits contain a common flavone glycoside that has specific pharmacological and biological properties. Naringin, a flavone glycoside with a range of intriguing characteristics, is abundant in citrus fruits. Naringin has been shown to have a variety of biological, medicinal, and pharmacological effects. Naringin is hydrolyzed into rhamnose and prunin by the naringinase, which also possesses l-rhamnosidase activity. D-glucosidase subsequently catalyzes the hydrolysis of prunin into glucose and naringenin. Naringin is known for having anti-inflammatory, antioxidant, and tumor-fighting effects. Numerous test animals and cell lines have been used to correlate naringin exposure to asthma, hyperlipidemia, diabetes, cancer, hyperthyroidism, and osteoporosis. This study focused on the many documented actions of naringin in in-vitro and in-vivo experimental and preclinical investigations, as well as its prospective therapeutic advantages, utilizing the information that is presently accessible in the literature. In addition to its pharmacokinetic characteristics, naringin’s structure, distribution, different extraction methods, and potential use in the cosmetic, food, pharmaceutical, and animal feed sectors were discussed.
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spelling pubmed-104198722023-08-12 Phytochemical Properties, Extraction, and Pharmacological Benefits of Naringin: A Review Shilpa, VS Shams, Rafeeya Dash, Kshirod Kumar Pandey, Vinay Kumar Dar, Aamir Hussain Ayaz Mukarram, Shaikh Harsányi, Endre Kovács, Béla Molecules Review This review describes the various innovative approaches implemented for naringin extraction as well as the recent developments in the field. Naringin was assessed in terms of its structure, chemical composition, and potential food sources. How naringin works pharmacologically was discussed, including its potential as an anti-diabetic, anti-inflammatory, and hepatoprotective substance. Citrus flavonoids are crucial herbal additives that have a huge spectrum of organic activities. Naringin is a nutritional flavanone glycoside that has been shown to be effective in the treatment of a few chronic disorders associated with ageing. Citrus fruits contain a common flavone glycoside that has specific pharmacological and biological properties. Naringin, a flavone glycoside with a range of intriguing characteristics, is abundant in citrus fruits. Naringin has been shown to have a variety of biological, medicinal, and pharmacological effects. Naringin is hydrolyzed into rhamnose and prunin by the naringinase, which also possesses l-rhamnosidase activity. D-glucosidase subsequently catalyzes the hydrolysis of prunin into glucose and naringenin. Naringin is known for having anti-inflammatory, antioxidant, and tumor-fighting effects. Numerous test animals and cell lines have been used to correlate naringin exposure to asthma, hyperlipidemia, diabetes, cancer, hyperthyroidism, and osteoporosis. This study focused on the many documented actions of naringin in in-vitro and in-vivo experimental and preclinical investigations, as well as its prospective therapeutic advantages, utilizing the information that is presently accessible in the literature. In addition to its pharmacokinetic characteristics, naringin’s structure, distribution, different extraction methods, and potential use in the cosmetic, food, pharmaceutical, and animal feed sectors were discussed. MDPI 2023-07-25 /pmc/articles/PMC10419872/ /pubmed/37570594 http://dx.doi.org/10.3390/molecules28155623 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Shilpa, VS
Shams, Rafeeya
Dash, Kshirod Kumar
Pandey, Vinay Kumar
Dar, Aamir Hussain
Ayaz Mukarram, Shaikh
Harsányi, Endre
Kovács, Béla
Phytochemical Properties, Extraction, and Pharmacological Benefits of Naringin: A Review
title Phytochemical Properties, Extraction, and Pharmacological Benefits of Naringin: A Review
title_full Phytochemical Properties, Extraction, and Pharmacological Benefits of Naringin: A Review
title_fullStr Phytochemical Properties, Extraction, and Pharmacological Benefits of Naringin: A Review
title_full_unstemmed Phytochemical Properties, Extraction, and Pharmacological Benefits of Naringin: A Review
title_short Phytochemical Properties, Extraction, and Pharmacological Benefits of Naringin: A Review
title_sort phytochemical properties, extraction, and pharmacological benefits of naringin: a review
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10419872/
https://www.ncbi.nlm.nih.gov/pubmed/37570594
http://dx.doi.org/10.3390/molecules28155623
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