Development of tolerance to chemokine receptor antagonists: current paradigms and the need for further investigation

Chemokine G-protein coupled receptors are validated drug targets for many diseases, including cancer, neurological, and inflammatory disorders. Despite much time and effort spent on therapeutic development, very few chemokine receptor antagonists are approved for clinical use. Among potential reason...

Descripción completa

Detalles Bibliográficos
Autores principales: Grudzien, Patrick, Neufeld, Henry, Ebe Eyenga, Mbasogo, Gaponenko, Vadim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10420067/
https://www.ncbi.nlm.nih.gov/pubmed/37575219
http://dx.doi.org/10.3389/fimmu.2023.1184014

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10420067/
https://www.ncbi.nlm.nih.gov/pubmed/37575219
http://dx.doi.org/10.3389/fimmu.2023.1184014

Ejemplares similares